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NNMT: Mean-Field Based Analysis Tools for Neuronal Network Models

Mean-field theory of neuronal networks has led to numerous advances in our analytical and intuitive understanding of their dynamics during the past decades. In order to make mean-field based analysis tools more accessible, we implemented an extensible, easy-to-use open-source Python toolbox that col...

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Autores principales: Layer, Moritz, Senk, Johanna, Essink, Simon, van Meegen, Alexander, Bos, Hannah, Helias, Moritz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9196133/
https://www.ncbi.nlm.nih.gov/pubmed/35712677
http://dx.doi.org/10.3389/fninf.2022.835657
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author Layer, Moritz
Senk, Johanna
Essink, Simon
van Meegen, Alexander
Bos, Hannah
Helias, Moritz
author_facet Layer, Moritz
Senk, Johanna
Essink, Simon
van Meegen, Alexander
Bos, Hannah
Helias, Moritz
author_sort Layer, Moritz
collection PubMed
description Mean-field theory of neuronal networks has led to numerous advances in our analytical and intuitive understanding of their dynamics during the past decades. In order to make mean-field based analysis tools more accessible, we implemented an extensible, easy-to-use open-source Python toolbox that collects a variety of mean-field methods for the leaky integrate-and-fire neuron model. The Neuronal Network Mean-field Toolbox (NNMT) in its current state allows for estimating properties of large neuronal networks, such as firing rates, power spectra, and dynamical stability in mean-field and linear response approximation, without running simulations. In this article, we describe how the toolbox is implemented, show how it is used to reproduce results of previous studies, and discuss different use-cases, such as parameter space explorations, or mapping different network models. Although the initial version of the toolbox focuses on methods for leaky integrate-and-fire neurons, its structure is designed to be open and extensible. It aims to provide a platform for collecting analytical methods for neuronal network model analysis, such that the neuroscientific community can take maximal advantage of them.
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spelling pubmed-91961332022-06-15 NNMT: Mean-Field Based Analysis Tools for Neuronal Network Models Layer, Moritz Senk, Johanna Essink, Simon van Meegen, Alexander Bos, Hannah Helias, Moritz Front Neuroinform Neuroscience Mean-field theory of neuronal networks has led to numerous advances in our analytical and intuitive understanding of their dynamics during the past decades. In order to make mean-field based analysis tools more accessible, we implemented an extensible, easy-to-use open-source Python toolbox that collects a variety of mean-field methods for the leaky integrate-and-fire neuron model. The Neuronal Network Mean-field Toolbox (NNMT) in its current state allows for estimating properties of large neuronal networks, such as firing rates, power spectra, and dynamical stability in mean-field and linear response approximation, without running simulations. In this article, we describe how the toolbox is implemented, show how it is used to reproduce results of previous studies, and discuss different use-cases, such as parameter space explorations, or mapping different network models. Although the initial version of the toolbox focuses on methods for leaky integrate-and-fire neurons, its structure is designed to be open and extensible. It aims to provide a platform for collecting analytical methods for neuronal network model analysis, such that the neuroscientific community can take maximal advantage of them. Frontiers Media S.A. 2022-05-27 /pmc/articles/PMC9196133/ /pubmed/35712677 http://dx.doi.org/10.3389/fninf.2022.835657 Text en Copyright © 2022 Layer, Senk, Essink, van Meegen, Bos and Helias. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Layer, Moritz
Senk, Johanna
Essink, Simon
van Meegen, Alexander
Bos, Hannah
Helias, Moritz
NNMT: Mean-Field Based Analysis Tools for Neuronal Network Models
title NNMT: Mean-Field Based Analysis Tools for Neuronal Network Models
title_full NNMT: Mean-Field Based Analysis Tools for Neuronal Network Models
title_fullStr NNMT: Mean-Field Based Analysis Tools for Neuronal Network Models
title_full_unstemmed NNMT: Mean-Field Based Analysis Tools for Neuronal Network Models
title_short NNMT: Mean-Field Based Analysis Tools for Neuronal Network Models
title_sort nnmt: mean-field based analysis tools for neuronal network models
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9196133/
https://www.ncbi.nlm.nih.gov/pubmed/35712677
http://dx.doi.org/10.3389/fninf.2022.835657
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