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Clinical and videourodynamic study characteristics in female primary bladder neck obstruction and outcomes of bladder neck resection: A tertiary care center experience in India

INTRODUCTION: Video urodynamic study (VUDS) with clinical correlation helps in diagnosing primary bladder neck obstruction (PBNO) in women. Bladder neck incision/bladder neck resection (BNR) though effective is not commonly practiced for the fear of complications and limited literature available. ME...

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Autores principales: Kalra, Sidhartha, Bokka, Sri Harsha, Dorairajan, Lalgudi Narayanan, Manikandan, Ramanitharan, Sreerag, KS, Jagannath, Avinash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9197009/
https://www.ncbi.nlm.nih.gov/pubmed/35711475
http://dx.doi.org/10.4103/UA.UA_108_20
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author Kalra, Sidhartha
Bokka, Sri Harsha
Dorairajan, Lalgudi Narayanan
Manikandan, Ramanitharan
Sreerag, KS
Jagannath, Avinash
author_facet Kalra, Sidhartha
Bokka, Sri Harsha
Dorairajan, Lalgudi Narayanan
Manikandan, Ramanitharan
Sreerag, KS
Jagannath, Avinash
author_sort Kalra, Sidhartha
collection PubMed
description INTRODUCTION: Video urodynamic study (VUDS) with clinical correlation helps in diagnosing primary bladder neck obstruction (PBNO) in women. Bladder neck incision/bladder neck resection (BNR) though effective is not commonly practiced for the fear of complications and limited literature available. METHODS: The records of ten women diagnosed with PBNO between 2017 and 2019 were reviewed and data pertaining to their clinical features, laboratory results, findings on abdominal ultrasonography, uroflowmetry, and VUDS was noted. Type of operative procedure performed and outcomes on follow-up were also assessed. RESULTS: Out of ten patients, two presented with lower urinary tract symptoms (LUTS), three with voiding LUTS and chronic retention and five had acute urinary retention. Mean serum creatinine was 3.4 mg/dl. In those able to void, mean maximum flow rate (Q max) was 7 ml/sec, and mean postvoid residual volume (PVR) was 360 ml. On VUDS, mean detrusor pressure at maximum flow (pdet@Qmax) was 54.2 cm of H20. Three patients opted conservative treatment and 7 had a successful surgical outcome with mean Q max of 26.2 ml/s (range: 13.9–41 ml/s), insignificant PVR and resolution of renal failure. Patients with pdet@Qmax <20 cm H(2)O (n = 3, mean 18.3 cm H(2)O) did equally well as compared to those with pdet@Qmax >20 cm H(2)O (n = 4, mean 93 cm H(2)O). None of the patients developed any complications on follow-up. CONCLUSIONS: Clinical assessment supported with VUDS correlation holds a key in identifying patients with PBNO. BNR is a safe and effective treatment of PBNO in women who fail or are not candidates for conservative treatment.
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spelling pubmed-91970092022-06-15 Clinical and videourodynamic study characteristics in female primary bladder neck obstruction and outcomes of bladder neck resection: A tertiary care center experience in India Kalra, Sidhartha Bokka, Sri Harsha Dorairajan, Lalgudi Narayanan Manikandan, Ramanitharan Sreerag, KS Jagannath, Avinash Urol Ann Original Article INTRODUCTION: Video urodynamic study (VUDS) with clinical correlation helps in diagnosing primary bladder neck obstruction (PBNO) in women. Bladder neck incision/bladder neck resection (BNR) though effective is not commonly practiced for the fear of complications and limited literature available. METHODS: The records of ten women diagnosed with PBNO between 2017 and 2019 were reviewed and data pertaining to their clinical features, laboratory results, findings on abdominal ultrasonography, uroflowmetry, and VUDS was noted. Type of operative procedure performed and outcomes on follow-up were also assessed. RESULTS: Out of ten patients, two presented with lower urinary tract symptoms (LUTS), three with voiding LUTS and chronic retention and five had acute urinary retention. Mean serum creatinine was 3.4 mg/dl. In those able to void, mean maximum flow rate (Q max) was 7 ml/sec, and mean postvoid residual volume (PVR) was 360 ml. On VUDS, mean detrusor pressure at maximum flow (pdet@Qmax) was 54.2 cm of H20. Three patients opted conservative treatment and 7 had a successful surgical outcome with mean Q max of 26.2 ml/s (range: 13.9–41 ml/s), insignificant PVR and resolution of renal failure. Patients with pdet@Qmax <20 cm H(2)O (n = 3, mean 18.3 cm H(2)O) did equally well as compared to those with pdet@Qmax >20 cm H(2)O (n = 4, mean 93 cm H(2)O). None of the patients developed any complications on follow-up. CONCLUSIONS: Clinical assessment supported with VUDS correlation holds a key in identifying patients with PBNO. BNR is a safe and effective treatment of PBNO in women who fail or are not candidates for conservative treatment. Wolters Kluwer - Medknow 2022 2022-02-15 /pmc/articles/PMC9197009/ /pubmed/35711475 http://dx.doi.org/10.4103/UA.UA_108_20 Text en Copyright: © 2022 Urology Annals https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Kalra, Sidhartha
Bokka, Sri Harsha
Dorairajan, Lalgudi Narayanan
Manikandan, Ramanitharan
Sreerag, KS
Jagannath, Avinash
Clinical and videourodynamic study characteristics in female primary bladder neck obstruction and outcomes of bladder neck resection: A tertiary care center experience in India
title Clinical and videourodynamic study characteristics in female primary bladder neck obstruction and outcomes of bladder neck resection: A tertiary care center experience in India
title_full Clinical and videourodynamic study characteristics in female primary bladder neck obstruction and outcomes of bladder neck resection: A tertiary care center experience in India
title_fullStr Clinical and videourodynamic study characteristics in female primary bladder neck obstruction and outcomes of bladder neck resection: A tertiary care center experience in India
title_full_unstemmed Clinical and videourodynamic study characteristics in female primary bladder neck obstruction and outcomes of bladder neck resection: A tertiary care center experience in India
title_short Clinical and videourodynamic study characteristics in female primary bladder neck obstruction and outcomes of bladder neck resection: A tertiary care center experience in India
title_sort clinical and videourodynamic study characteristics in female primary bladder neck obstruction and outcomes of bladder neck resection: a tertiary care center experience in india
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9197009/
https://www.ncbi.nlm.nih.gov/pubmed/35711475
http://dx.doi.org/10.4103/UA.UA_108_20
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