Cargando…

The Role of DOT1L in Normal and Malignant Hematopoiesis

Disruptor of telomeric silencing 1 (DOT1) was first identified in yeast (DOT1p) and is the sole methyltransferase responsible for histone three lysine 79 (H3K79) mono-, di-, and tri-methylation. Mammalian DOT1 (DOT1-like protein or DOT1L) has been implicated in many cellular processes, such as cell...

Descripción completa

Detalles Bibliográficos
Autores principales:	Arnold, Olivia, Barbosa, Karina, Deshpande, Aniruddha J., Zhu, Nan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9197164/ https://www.ncbi.nlm.nih.gov/pubmed/35712672 http://dx.doi.org/10.3389/fcell.2022.917125

Ejemplares similares

RNA m(6)A Modification Plays a Key Role in Maintaining Stem Cell Function in Normal and Malignant Hematopoiesis
por: Wang, Peipei, et al.
Publicado: (2021)

Role of SVEP1 in Stroma-Dependent Hematopoiesis In vitro
por: Tran, Vinson, et al.
Publicado: (2022)

The Opportunity of Proteomics to Advance the Understanding of Intra- and Extracellular Regulation of Malignant Hematopoiesis
por: Jassinskaja, Maria, et al.
Publicado: (2022)

The role of GATA2 in adult hematopoiesis and cell fate determination
por: Peters, Iris J. A., et al.
Publicado: (2023)

Mouse Yolk Sac Hematopoiesis
por: Yamane, Toshiyuki
Publicado: (2018)

KIT Is Required for Fetal Liver Hematopoiesis
por: Fantin, Alessandro, et al.
Publicado: (2021)

Vascular Notch Signaling in Stress Hematopoiesis
por: Huang, Can, et al.
Publicado: (2021)

JAK-STAT in Early Hematopoiesis and Leukemia
por: Fasouli, Eirini Sofia, et al.
Publicado: (2021)

Epigenetic roles in clonal hematopoiesis and aging kidney-related chronic kidney disease
por: Ogura, Yoshiyasu, et al.
Publicado: (2023)

Lessons to cancer from studies of leukemia and hematopoiesis
por: Brown, Geoffrey
Publicado: (2022)

Primitive Erythropoiesis in the Mouse is Independent of DOT1L Methyltransferase Activity
por: Malcom, Carrie A., et al.
Publicado: (2022)

Wild-Type p53-Induced Phosphatase 1 Plays a Positive Role in Hematopoiesis in the Mouse Embryonic Head
por: He, Wenyan, et al.
Publicado: (2021)

Hematopoiesis: A Layered Organization Across Chordate Species
por: Elsaid, Ramy, et al.
Publicado: (2020)

Common and distinct functions of mouse Dot1l in the regulation of endothelial transcriptome
por: Yoo, Hyunjin, et al.
Publicado: (2023)

The Ribosome Biogenesis Factor Ltv1 Is Essential for Digestive Organ Development and Definitive Hematopoiesis in Zebrafish
por: Zhang, Chong, et al.
Publicado: (2021)

Contributions of Embryonic HSC-Independent Hematopoiesis to Organogenesis and the Adult Hematopoietic System
por: Neo, Wen Hao, et al.
Publicado: (2021)

Stem Cells, Hematopoiesis and Lineage Tracing: Transplantation-Centric Views and Beyond
por: Konturek-Ciesla, Anna, et al.
Publicado: (2022)

Embryonic hematopoiesis modulates the inflammatory response and larval hematopoiesis in Drosophila
por: Bazzi, Wael, et al.
Publicado: (2018)

Three-Dimensional Models as a New Frontier for Studying the Role of Proteoglycans in the Normal and Malignant Breast Microenvironment
por: Clegg, Julien, et al.
Publicado: (2020)

Editorial: The Bone Marrow Niche in Normal and Malignant Haematopoiesis
por: Colombo, Michela, et al.
Publicado: (2022)

Altered Erythro-Myeloid Progenitor Cells Are Highly Expanded in Intensively Regenerating Hematopoiesis
por: Faltusová, Kateřina, et al.
Publicado: (2020)

Epigenetic regulation of hematopoiesis by DNA methylation
por: Gore, Aniket V, et al.
Publicado: (2016)

Surface decorated quantum dots: Synthesis, properties and role in herbal therapy
por: Baig, Mirza Shahed, et al.
Publicado: (2023)

Mutation of Gemin5 Causes Defective Hematopoietic Stem/Progenitor Cells Proliferation in Zebrafish Embryonic Hematopoiesis
por: Liu, Xiaofen, et al.
Publicado: (2021)

Hematopoiesis Remains Permissive to Bone Marrow Transplantation After Expansion of Progenitors and Resumption of Blood Cell Production
por: Báječný, Martin, et al.
Publicado: (2021)

A Comprehensive Characterization of Monoallelic Expression During Hematopoiesis and Leukemogenesis via Single-Cell RNA-Sequencing
por: Fu, Ruiqing, et al.
Publicado: (2021)

Phospho-Site Mutations in Transcription Factor Suppressor of Hairless Impact Notch Signaling Activity During Hematopoiesis in Drosophila
por: Frankenreiter, Lisa, et al.
Publicado: (2021)

Connecting the DOTs on Cell Identity
por: Wille, Coral K., et al.
Publicado: (2022)

Absence of Nkx2-3 induces ectopic lymphatic endothelial differentiation associated with impaired extramedullary stress hematopoiesis in the spleen
por: Gábris, Fanni, et al.
Publicado: (2023)

Role of HDACs in normal and malignant hematopoiesis
por: Wang, Pan, et al.
Publicado: (2020)

Symbiont-induced odorant binding proteins mediate insect host hematopoiesis
por: Benoit, Joshua B, et al.
Publicado: (2017)

Molecular and epigenetic alterations in normal and malignant myelopoiesis in human leukemia 60 (HL60) promyelocytic cell line model
por: Basu, Jhinuk, et al.
Publicado: (2023)

Connecting the Dots: Resolving the Bone Marrow Niche Heterogeneity
por: Dolgalev, Igor, et al.
Publicado: (2021)

The role of NLRP3 inflammasome in digestive system malignancy
por: Sun, Cen-Cen, et al.
Publicado: (2022)

Role of the Bone Marrow Niche in Supporting the Pathogenesis of Lymphoid Malignancies
por: Jalali, Shahrzad, et al.
Publicado: (2021)

An Update on the Roles of circRNA-ZFR in Human Malignant Tumors
por: Liu, Lang, et al.
Publicado: (2022)

A Role for Malignant Brain Tumor Domain-Containing Protein 1 in Human Endometrial Stromal Cell Decidualization
por: Chadchan, Sangappa B., et al.
Publicado: (2020)

The Role of MicroRNAs in Therapeutic Resistance of Malignant Primary Brain Tumors
por: Gareev, Ilgiz, et al.
Publicado: (2021)

Stathmin 1 in normal and malignant hematopoiesis
por: Machado-Neto, João Agostinho, et al.
Publicado: (2014)

MCM5 Aggravates the HDAC1-Mediated Malignant Progression of Lung Cancer
por: Zhang, Lin-lin, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_i1mtpgpk56b2eova89esnh5l8n