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Statin Treatment as a Targeted Therapy for APC-Mutated Colorectal Cancer

BACKGROUND: Mutations in the tumor suppressor gene Adenomatous Polyposis Coli (APC) are found in 80% of sporadic colorectal cancer (CRC) tumors and are also responsible for the inherited form of CRC, Familial adenomatous polyposis (FAP). METHODS: To identify novel therapeutic strategies for the trea...

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Detalles Bibliográficos
Autores principales:	Shailes, Hannah, Tse, Wai Yiu, Freitas, Marta O., Silver, Andrew, Martin, Sarah A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9197185/ https://www.ncbi.nlm.nih.gov/pubmed/35712511 http://dx.doi.org/10.3389/fonc.2022.880552

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