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A Simple and Robust Single-Step Method for CAR-Vδ1 γδT Cell Expansion and Transduction for Cancer Immunotherapy

The γδT cell subset of peripheral lymphocytes exhibits potent cancer antigen recognition independent of classical peptide MHC complexes, making it an attractive candidate for allogeneic cancer adoptive immunotherapy. The Vδ1-T cell receptor (TCR)-expressing subset of peripheral γδT cells has remaine...

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Detalles Bibliográficos
Autores principales: Ferry, Gabrielle M., Agbuduwe, Charles, Forrester, Megan, Dunlop, Sophie, Chester, Kerry, Fisher, Jonathan, Anderson, John, Barisa, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9197253/
https://www.ncbi.nlm.nih.gov/pubmed/35711450
http://dx.doi.org/10.3389/fimmu.2022.863155