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Immunoglobulin Heavy Chain High-Throughput Sequencing in Pediatric B-Precursor Acute Lymphoblastic Leukemia: Is the Clonality of the Disease at Diagnosis Related to Its Prognosis?
High-throughput sequencing (HTS) of the immunoglobulin heavy chain (IgH) locus is a recent very efficient technique to monitor minimal residual disease of B-cell precursor acute lymphoblastic leukemia (BCP-ALL). It also reveals the sequences of clonal rearrangements, therefore, the multiclonal struc...
Autores principales: | Levy, Gabriel, Kicinski, Michal, Van der Straeten, Jona, Uyttebroeck, Anne, Ferster, Alina, De Moerloose, Barbara, Dresse, Marie-Francoise, Chantrain, Christophe, Brichard, Bénédicte, Bakkus, Marleen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9197340/ https://www.ncbi.nlm.nih.gov/pubmed/35712632 http://dx.doi.org/10.3389/fped.2022.874771 |
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