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Immunoglobulin Heavy Chain High-Throughput Sequencing in Pediatric B-Precursor Acute Lymphoblastic Leukemia: Is the Clonality of the Disease at Diagnosis Related to Its Prognosis?

High-throughput sequencing (HTS) of the immunoglobulin heavy chain (IgH) locus is a recent very efficient technique to monitor minimal residual disease of B-cell precursor acute lymphoblastic leukemia (BCP-ALL). It also reveals the sequences of clonal rearrangements, therefore, the multiclonal struc...

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Detalles Bibliográficos
Autores principales: Levy, Gabriel, Kicinski, Michal, Van der Straeten, Jona, Uyttebroeck, Anne, Ferster, Alina, De Moerloose, Barbara, Dresse, Marie-Francoise, Chantrain, Christophe, Brichard, Bénédicte, Bakkus, Marleen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9197340/
https://www.ncbi.nlm.nih.gov/pubmed/35712632
http://dx.doi.org/10.3389/fped.2022.874771

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