Cargando…

Immunoproteasome Inhibition Reduces the T Helper 2 Response in Mouse Models of Allergic Airway Inflammation

BACKGROUND: Allergic asthma is a chronic disease and medical treatment often fails to fully control the disease in the long term, leading to a great need for new therapeutic approaches. Immunoproteasome inhibition impairs T helper cell function and is effective in many (auto-) inflammatory settings...

Descripción completa

Detalles Bibliográficos
Autores principales:	Oliveri, Franziska, Basler, Michael, Rao, Tata Nageswara, Fehling, Hans Joerg, Groettrup, Marcus
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9197384/ https://www.ncbi.nlm.nih.gov/pubmed/35711460 http://dx.doi.org/10.3389/fimmu.2022.870720

Ejemplares similares

Immunoproteasome Inhibition Impairs T and B Cell Activation by Restraining ERK Signaling and Proteostasis
por: Schmidt, Christian, et al.
Publicado: (2018)

On the Role of the Immunoproteasome in Protein Homeostasis
por: Basler, Michael, et al.
Publicado: (2021)

Inhibiting the immunoproteasome exacerbates the pathogenesis of systemic Candida albicans infection in mice
por: Mundt, Sarah, et al.
Publicado: (2016)

Inhibition of the immunoproteasome ameliorates experimental autoimmune encephalomyelitis
por: Basler, Michael, et al.
Publicado: (2014)

Group 2 Innate Lymphoid Cells Exhibit a Dynamic Phenotype in Allergic Airway Inflammation
por: Li, Bobby W. S., et al.
Publicado: (2017)

Immunoproteasome inhibition attenuates experimental psoriasis
por: del Rio Oliva, Marta, et al.
Publicado: (2022)

The Pioneer Transcription Factor Foxa2 Modulates T Helper Differentiation to Reduce Mouse Allergic Airway Disease
por: Yánez, Diana C., et al.
Publicado: (2022)

Suppression of prostate cancer and amelioration of the immunosuppressive tumor microenvironment through selective immunoproteasome inhibition
por: Koerner, Julia, et al.
Publicado: (2022)

Inhibition and deficiency of the immunoproteasome subunit LMP7 suppress the development and progression of colorectal carcinoma in mice
por: Koerner, Julia, et al.
Publicado: (2017)

Ascaris lumbricoides Cystatin Prevents Development of Allergic Airway Inflammation in a Mouse Model
por: Coronado, Sandra, et al.
Publicado: (2019)

Differential Regulation of Allergic Airway Inflammation by Acetylcholine
por: Roberts, Luke B., et al.
Publicado: (2022)

Chronic, Elevated Maternal Corticosterone During Pregnancy in the Mouse Increases Allergic Airway Inflammation in Offspring
por: Smith, Arianna L., et al.
Publicado: (2020)

Editorial: Role of Lipids in the Dynamics of Allergic Airway Inflammation
por: González Roldán, Nestor, et al.
Publicado: (2020)

Neuro-Immune Regulation in Inflammation and Airway Remodeling of Allergic Asthma
por: Zhang, Ning, et al.
Publicado: (2022)

Critical Involvement of CD44 in T Helper Type 2 Cell-Mediated Eosinophilic Airway Inflammation in a Mouse Model of Acute Asthma
por: Katoh, Shigeki
Publicado: (2022)

Pollen Lipids Can Play a Role in Allergic Airway Inflammation
por: Dahl, Åslög
Publicado: (2018)

Phloretin Attenuates Allergic Airway Inflammation and Oxidative Stress in Asthmatic Mice
por: Huang, Wen-Chung, et al.
Publicado: (2017)

Systemic Pharmacological Smoothened Inhibition Reduces Lung T-Cell Infiltration and Ameliorates Th2 Inflammation in a Mouse Model of Allergic Airway Disease
por: Yánez, Diana C., et al.
Publicado: (2021)

T Helper 1 Cells and Interferon γ Regulate Allergic Airway Inflammation and Mucus Production
por: Cohn, Lauren, et al.
Publicado: (1999)

Corrigendum: Phloretin Attenuates Allergic Airway Inflammation and Oxidative Stress in Asthmatic Mice
por: Huang, Wen-Chung, et al.
Publicado: (2020)

Immunoproteasomes control activation of innate immune signaling and microglial function
por: Çetin, Gonca, et al.
Publicado: (2022)

Melatonin prevents allergic airway inflammation in epicutaneously sensitized mice
por: Liu, Xudong, et al.
Publicado: (2021)

Maternal Lactobacillus rhamnosus administration impacts neonatal CD4 T-cell activation and prevents murine T helper 2-type allergic airways disease
por: Smout, Justine, et al.
Publicado: (2023)

Immune Cell-Epithelial/Mesenchymal Interaction Contributing to Allergic Airway Inflammation Associated Pathology
por: Hirahara, Kiyoshi, et al.
Publicado: (2019)

Modulation of Allergic Sensitization and Allergic Inflammation by Staphylococcus aureus Enterotoxin B in an Ovalbumin Mouse Model
por: Jorde, Ilka, et al.
Publicado: (2020)

IFITM proteins drive type 2 T helper cell differentiation and exacerbate allergic airway inflammation
por: Yánez, Diana C., et al.
Publicado: (2018)

Impact of Enhancer of Zeste Homolog 2 on T Helper Cell-Mediated Allergic Rhinitis
por: Hou, Tsung-Yun, et al.
Publicado: (2017)

Non-redundant Functions of IL-6 Produced by Macrophages and Dendritic Cells in Allergic Airway Inflammation
por: Gubernatorova, Ekaterina O., et al.
Publicado: (2018)

Vanadium exposure exacerbates allergic airway inflammation and remodeling through triggering reactive oxidative stress
por: Tu, Wei, et al.
Publicado: (2023)

Transfer factors peptides (Imuno TF(®)) modulate the lung inflammation and airway remodeling in allergic asthma
por: Oliveira, Carlos Rocha, et al.
Publicado: (2023)

The Role of Lectin Receptors and Their Ligands in Controlling Allergic Inflammation
por: Peters, Karin, et al.
Publicado: (2021)

Critical Roles of Balanced T Helper 9 Cells and Regulatory T Cells in Allergic Airway Inflammation and Tumor Immunity
por: Huang, Muhua, et al.
Publicado: (2021)

IL-17 and TNF-α Are Key Mediators of Moraxella catarrhalis Triggered Exacerbation of Allergic Airway Inflammation
por: Alnahas, Safa, et al.
Publicado: (2017)

Endothelin-A Receptor Antagonist Alleviates Allergic Airway Inflammation via the Inhibition of ILC2 Function
por: Zhang, Xiaogang, et al.
Publicado: (2022)

Free Feeding of CpG-Oligodeoxynucleotide Particles Prophylactically Attenuates Allergic Airway Inflammation and Hyperresponsiveness in Mice
por: Okajima, Takuma, et al.
Publicado: (2021)

Lung Epithelial CYP1 Activity Regulates Aryl Hydrocarbon Receptor Dependent Allergic Airway Inflammation
por: Alessandrini, Francesca, et al.
Publicado: (2022)

Co-Inhibition of the Immunoproteasome Subunits LMP2 and LMP7 Ameliorates Immune Thrombocytopenia
por: Du, Sheng-hong, et al.
Publicado: (2021)

Metabolic Checkpoints in Differentiation of Helper T Cells in Tissue Inflammation
por: Roy, Suyasha, et al.
Publicado: (2019)

Chimeric Antigen Receptor-Redirected Regulatory T Cells Suppress Experimental Allergic Airway Inflammation, a Model of Asthma
por: Skuljec, Jelena, et al.
Publicado: (2017)

TLR2-Melatonin Feedback Loop Regulates the Activation of NLRP3 Inflammasome in Murine Allergic Airway Inflammation
por: Wu, Hui-Mei, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_d2k70c1hqfl0tk3btog9ea86lk