Central tolerance is impaired in the middle‐aged thymic environment

One of the earliest hallmarks of immune aging is thymus involution, which not only reduces the number of newly generated and exported T cells, but also alters the composition and organization of the thymus microenvironment. Thymic T‐cell export continues into adulthood, yet the impact of thymus invo...

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Detalles Bibliográficos
Autores principales: Lancaster, Jessica N., Keatinge‐Clay, Damaris E., Srinivasan, Jayashree, Li, Yu, Selden, Hilary J., Nam, Seohee, Richie, Ellen R., Ehrlich, Lauren I. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9197411/
https://www.ncbi.nlm.nih.gov/pubmed/35561351
http://dx.doi.org/10.1111/acel.13624

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9197411/
https://www.ncbi.nlm.nih.gov/pubmed/35561351
http://dx.doi.org/10.1111/acel.13624

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