Integrative analysis of clinical and epigenetic biomarkers of mortality

DNA methylation (DNAm) has been reported to be associated with many diseases and with mortality. We hypothesized that the integration of DNAm with clinical risk factors would improve mortality prediction. We performed an epigenome‐wide association study of whole blood DNAm in relation to mortality i...

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Detalles Bibliográficos
Autores principales: Huan, Tianxiao, Nguyen, Steve, Colicino, Elena, Ochoa‐Rosales, Carolina, Hill, W. David, Brody, Jennifer A., Soerensen, Mette, Zhang, Yan, Baldassari, Antoine, Elhadad, Mohamed Ahmed, Toshiko, Tanaka, Zheng, Yinan, Domingo‐Relloso, Arce, Lee, Dong Heon, Ma, Jiantao, Yao, Chen, Liu, Chunyu, Hwang, Shih‐Jen, Joehanes, Roby, Fornage, Myriam, Bressler, Jan, van Meurs, Joyce B.J., Debrabant, Birgit, Mengel‐From, Jonas, Hjelmborg, Jacob, Christensen, Kaare, Vokonas, Pantel, Schwartz, Joel, Gahrib, Sina A., Sotoodehnia, Nona, Sitlani, Colleen M., Kunze, Sonja, Gieger, Christian, Peters, Annette, Waldenberger, Melanie, Deary, Ian J., Ferrucci, Luigi, Qu, Yishu, Greenland, Philip, Lloyd‐Jones, Donald M., Hou, Lifang, Bandinelli, Stefania, Voortman, Trudy, Hermann, Brenner, Baccarelli, Andrea, Whitsel, Eric, Pankow, James S., Levy, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9197414/
https://www.ncbi.nlm.nih.gov/pubmed/35546478
http://dx.doi.org/10.1111/acel.13608

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