High-affinity autoreactive plasma cells disseminate through multiple organs in patients with immune thrombocytopenic purpura

The major therapeutic goal for immune thrombocytopenic purpura (ITP) is to restore normal platelet counts using drugs to promote platelet production or by interfering with mechanisms responsible for platelet destruction. Eighty percent of patients with ITP possess anti–integrin αIIbβ3 IgG autoantibo...

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Detalles Bibliográficos
Autores principales: Canales-Herrerias, Pablo, Crickx, Etienne, Broketa, Matteo, Sokal, Aurélien, Chenon, Guilhem, Azzaoui, Imane, Vandenberghe, Alexis, Perima, Angga, Iannascoli, Bruno, Richard-Le Goff, Odile, Castrillon, Carlos, Mottet, Guillaume, Sterlin, Delphine, Robbins, Ailsa, Michel, Marc, England, Patrick, Millot, Gael A., Eyer, Klaus, Baudry, Jean, Mahevas, Matthieu, Bruhns, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9197514/
https://www.ncbi.nlm.nih.gov/pubmed/35503254
http://dx.doi.org/10.1172/JCI153580

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9197514/
https://www.ncbi.nlm.nih.gov/pubmed/35503254
http://dx.doi.org/10.1172/JCI153580

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