IL-33 acts as a costimulatory signal to generate alloreactive Th1 cells in graft-versus-host disease

Antigen-presenting cells (APCs) integrate signals emanating from local pathology and program appropriate T cell responses. In allogeneic hematopoietic stem cell transplantation (alloHCT), recipient conditioning releases damage-associated molecular patterns (DAMPs) that generate proinflammatory APCs...

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Detalles Bibliográficos
Autores principales: Dwyer, Gaelen K., Mathews, Lisa R., Villegas, José A., Lucas, Anna, Gonzalez de Peredo, Anne, Blazar, Bruce R., Girard, Jean-Philippe, Poholek, Amanda C., Luther, Sanjiv A., Shlomchik, Warren, Turnquist, Hēth R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9197517/
https://www.ncbi.nlm.nih.gov/pubmed/35503257
http://dx.doi.org/10.1172/JCI150927

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9197517/
https://www.ncbi.nlm.nih.gov/pubmed/35503257
http://dx.doi.org/10.1172/JCI150927

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