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IL-33 acts as a costimulatory signal to generate alloreactive Th1 cells in graft-versus-host disease
Antigen-presenting cells (APCs) integrate signals emanating from local pathology and program appropriate T cell responses. In allogeneic hematopoietic stem cell transplantation (alloHCT), recipient conditioning releases damage-associated molecular patterns (DAMPs) that generate proinflammatory APCs...
Autores principales: | Dwyer, Gaelen K., Mathews, Lisa R., Villegas, José A., Lucas, Anna, Gonzalez de Peredo, Anne, Blazar, Bruce R., Girard, Jean-Philippe, Poholek, Amanda C., Luther, Sanjiv A., Shlomchik, Warren, Turnquist, Hēth R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9197517/ https://www.ncbi.nlm.nih.gov/pubmed/35503257 http://dx.doi.org/10.1172/JCI150927 |
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