The microbiome restrains melanoma bone growth by promoting intestinal NK and Th1 cell homing to bone

Bone metastases are frequent complications of malignant melanoma leading to reduced quality of life and significant morbidity. Regulation of immune cells by the gut microbiome influences cancer progression, but the role of the microbiome in tumor growth in bone is unknown. Using intracardiac or intr...

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Detalles Bibliográficos
Autores principales: Pal, Subhashis, Perrien, Daniel S., Yumoto, Tetsuya, Faccio, Roberta, Stoica, Andreea, Adams, Jonathan, Coopersmith, Craig M., Jones, Rheinallt M., Weitzmann, M. Neale, Pacifici, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9197523/
https://www.ncbi.nlm.nih.gov/pubmed/35503658
http://dx.doi.org/10.1172/JCI157340

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