Cargando…
Characterization of the Role of Integrin α5β1 in Platelet Function, Hemostasis, and Experimental Thrombosis
Objective Integrins are key regulators of various platelet functions. The pathophysiological importance of most platelet integrins has been investigated, with the exception of α5β1, a receptor for fibronectin. The aim of this study was to characterize the role of α5β1 in megakaryopoiesis, platelet...
Autores principales: | Janus-Bell, Emily, Yakusheva, Alexandra, Scandola, Cyril, Receveur, Nicolas, Ahmed, Usman Muhammad, Mouriaux, Clarisse, Bourdon, Catherine, Loubière, Cécile, Eckly, Anita, Senis, Yotis A., Panteleev, Mikhail A., Gachet, Christian, Mangin, Pierre H. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Georg Thieme Verlag KG
2021
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9197593/ https://www.ncbi.nlm.nih.gov/pubmed/34598304 http://dx.doi.org/10.1055/a-1659-6214 |
Ejemplares similares
-
Traumatic vessel injuries initiating hemostasis generate high shear conditions
por: Yakusheva, Alexandra A., et al.
Publicado: (2022) -
The relative importance of platelet integrins in hemostasis, thrombosis and beyond
por: Janus-Bell, Emily, et al.
Publicado: (2023) -
Respective roles of Glycoprotein VI and FcγRIIA in the regulation of αIIbβ3‐mediated platelet activation to fibrinogen, thrombus buildup, and stability
por: Ahmed, Muhammad Usman, et al.
Publicado: (2021) -
Shear rate gradients promote a bi-phasic thrombus formation on weak adhesive proteins, such as fibrinogen in a von Willebrand factor-dependent manner
por: Receveur, Nicolas, et al.
Publicado: (2019) -
Platelet dysfunction and thrombus instability in flow conditions in patients with severe COVID-19
por: Tacquard, Charles, et al.
Publicado: (2023)