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Acquired Methemoglobinemia in a Ketamine-induced Ulcerative Cystitis Patient: A Case Report
INTRODUCTION: As ketamine gains traction as an alternative to opiates in the treatment of chronic pain, ketamine-induced ulcerative cystitis is now being recognized as a complication of its use. The first-line treatment is phenazopyridine, an over-the-counter medication for dysuria that historically...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
University of California Irvine, Department of Emergency Medicine publishing Western Journal of Emergency Medicine
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9197744/ https://www.ncbi.nlm.nih.gov/pubmed/35701344 http://dx.doi.org/10.5811/cpcem.2022.1.55277 |
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author | Kozik, Spencer Kirkham, Cali Sudario, Gabriel |
author_facet | Kozik, Spencer Kirkham, Cali Sudario, Gabriel |
author_sort | Kozik, Spencer |
collection | PubMed |
description | INTRODUCTION: As ketamine gains traction as an alternative to opiates in the treatment of chronic pain, ketamine-induced ulcerative cystitis is now being recognized as a complication of its use. The first-line treatment is phenazopyridine, an over-the-counter medication for dysuria that historically has been known to cause methemoglobinemia. This report details the case of a patient presenting to the emergency department (ED) with methemoglobinemia. CASE REPORT: A 66-year-old woman with a complicated medical history presented to the ED with anemia and hypoxia after extended use of phenazopyridine for treatment of ketamine-induced ulcerative cystitis. She was found to have methemoglobinemia secondary to phenazopyridine used to treat her ketamine-induced ulcerative cystitis, a previously undocumented sequelae of chronic ketamine use. She was admitted to the hospital for three days and made a full recovery. CONCLUSION: This case highlights the need to suspect ketamine-induced ulcerative cystitis in patients who use ketamine chronically and be judicious in the use of phenazopyridine for symptom management to prevent life-threatening complications. |
format | Online Article Text |
id | pubmed-9197744 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | University of California Irvine, Department of Emergency Medicine publishing Western Journal of Emergency Medicine |
record_format | MEDLINE/PubMed |
spelling | pubmed-91977442022-06-30 Acquired Methemoglobinemia in a Ketamine-induced Ulcerative Cystitis Patient: A Case Report Kozik, Spencer Kirkham, Cali Sudario, Gabriel Clin Pract Cases Emerg Med Case Report INTRODUCTION: As ketamine gains traction as an alternative to opiates in the treatment of chronic pain, ketamine-induced ulcerative cystitis is now being recognized as a complication of its use. The first-line treatment is phenazopyridine, an over-the-counter medication for dysuria that historically has been known to cause methemoglobinemia. This report details the case of a patient presenting to the emergency department (ED) with methemoglobinemia. CASE REPORT: A 66-year-old woman with a complicated medical history presented to the ED with anemia and hypoxia after extended use of phenazopyridine for treatment of ketamine-induced ulcerative cystitis. She was found to have methemoglobinemia secondary to phenazopyridine used to treat her ketamine-induced ulcerative cystitis, a previously undocumented sequelae of chronic ketamine use. She was admitted to the hospital for three days and made a full recovery. CONCLUSION: This case highlights the need to suspect ketamine-induced ulcerative cystitis in patients who use ketamine chronically and be judicious in the use of phenazopyridine for symptom management to prevent life-threatening complications. University of California Irvine, Department of Emergency Medicine publishing Western Journal of Emergency Medicine 2022-03-07 /pmc/articles/PMC9197744/ /pubmed/35701344 http://dx.doi.org/10.5811/cpcem.2022.1.55277 Text en © 2022 Kozik. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 4.0) License. See: http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) |
spellingShingle | Case Report Kozik, Spencer Kirkham, Cali Sudario, Gabriel Acquired Methemoglobinemia in a Ketamine-induced Ulcerative Cystitis Patient: A Case Report |
title | Acquired Methemoglobinemia in a Ketamine-induced Ulcerative Cystitis Patient: A Case Report |
title_full | Acquired Methemoglobinemia in a Ketamine-induced Ulcerative Cystitis Patient: A Case Report |
title_fullStr | Acquired Methemoglobinemia in a Ketamine-induced Ulcerative Cystitis Patient: A Case Report |
title_full_unstemmed | Acquired Methemoglobinemia in a Ketamine-induced Ulcerative Cystitis Patient: A Case Report |
title_short | Acquired Methemoglobinemia in a Ketamine-induced Ulcerative Cystitis Patient: A Case Report |
title_sort | acquired methemoglobinemia in a ketamine-induced ulcerative cystitis patient: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9197744/ https://www.ncbi.nlm.nih.gov/pubmed/35701344 http://dx.doi.org/10.5811/cpcem.2022.1.55277 |
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