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Treatment with Polyethylene Glycol–Conjugated Fungal d-Amino Acid Oxidase Reduces Lung Inflammation in a Mouse Model of Chronic Granulomatous Disease
Chronic granulomatous disease (CGD) is a primary immunodeficiency wherein phagocytes are unable to produce reactive oxygen species (ROS) owing to a defect in the nicotinamide adenine dinucleotide phosphate oxidase (NADPH) complex. Patients with CGD experience bacterial and fungal infections and exce...
Autores principales: | Nunoi, Hiroyuki, Xie, Peiyu, Nakamura, Hideaki, Aratani, Yasuaki, Fang, Jun, Nishimura, Toyoki, Kataoka, Hiroaki, Maeda, Hiroshi, Matsukura, Makoto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9197883/ https://www.ncbi.nlm.nih.gov/pubmed/35211862 http://dx.doi.org/10.1007/s10753-022-01650-z |
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