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CCL5 Release by CCR9+ CD8 T Cells: A Potential Contributor to Immunopathology of Primary Sjögren’s Syndrome

INTRODUCTION: Increased CCL5 expression and CD8 T cells have been shown to be pivotal regulators of immunopathology in primary Sjögren’s syndrome (pSS) and pSS-like disease. Increased CCL5 expression by CCR9+ CD4 T cells has previously been implicated as a contributor to immunopathology in pSS. The...

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Detalles Bibliográficos
Autores principales: Hinrichs, Anneline C., Blokland, Sofie L. M., Kruize, Aike A., Lafeber, Floris P. J., Leavis, Helen L., van Roon, Joel A. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9198220/
https://www.ncbi.nlm.nih.gov/pubmed/35720379
http://dx.doi.org/10.3389/fimmu.2022.887972