Evidence for a Prehypertensive Water Dysregulation Affecting the Development of Hypertension: Results of Very Early Treatment of Vasopressin V1 and V2 Antagonism in Spontaneously Hypertensive Rats

In addition to long-term regulation of blood pressure (BP), in the kidney resides the initial trigger for hypertension development due to an altered capacity to excrete sodium and water. Betaine is one of the major organic osmolytes, and its betaine/gamma-aminobutyric acid transporter (BGT-1) expres...

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Detalles Bibliográficos
Autores principales: Verzicco, Ignazio, Tedeschi, Stefano, Graiani, Gallia, Bongrani, Alice, Carnevali, Maria Luisa, Dancelli, Simona, Zappa, Jessica, Mattei, Silvia, Bovino, Achiropita, Cavazzini, Stefania, Rocco, Rossana, Calvi, Anna, Palladini, Barbara, Volpi, Riccardo, Cannone, Valentina, Coghi, Pietro, Borghetti, Alberico, Cabassi, Aderville
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9198251/
https://www.ncbi.nlm.nih.gov/pubmed/35722114
http://dx.doi.org/10.3389/fcvm.2022.897244

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