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Case Report: Treatment of Hypertrophic Cardiomyopathy With Stereotactic Body Radiotherapy

Patients with hypertrophic cardiomyopathy (HCM), which is characterized by left ventricular hypertrophy, is usually treated with medications such as calcium channel blockers or beta-blockers and invasive treatments such as transcatheter alcohol septal ablation, percutaneous radiofrequency ablation,...

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Autores principales: Xiao, Longzihui, Liu, Jiayi, Zhang, Yingzhe, Liu, Yuefei, Tang, Yan, Zhang, Minping, Ding, Zhuyuan, Xiao, Enhua, Chen, Taili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9198300/
https://www.ncbi.nlm.nih.gov/pubmed/35721064
http://dx.doi.org/10.3389/fmed.2022.799310
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author Xiao, Longzihui
Liu, Jiayi
Zhang, Yingzhe
Liu, Yuefei
Tang, Yan
Zhang, Minping
Ding, Zhuyuan
Xiao, Enhua
Chen, Taili
author_facet Xiao, Longzihui
Liu, Jiayi
Zhang, Yingzhe
Liu, Yuefei
Tang, Yan
Zhang, Minping
Ding, Zhuyuan
Xiao, Enhua
Chen, Taili
author_sort Xiao, Longzihui
collection PubMed
description Patients with hypertrophic cardiomyopathy (HCM), which is characterized by left ventricular hypertrophy, is usually treated with medications such as calcium channel blockers or beta-blockers and invasive treatments such as transcatheter alcohol septal ablation, percutaneous radiofrequency ablation, or heart transplantation. However, non-invasive methods have not been employed for the management of patients with HCM. A 71-year-old male who presented with occasional chest pain for approximately 2 months and had been diagnosed with HCM since he was 39 years old due to occasional fainting was treated with a novel method for HCM using stereotactic body radiotherapy (SBRT). The administration of 25 Gy of radiation as one fraction led to an improvement in his quality of life. No toxicity occurred during or immediately after the treatment. Our observations suggest that SBRT may be a reasonable treatment approach for patients with HCM who are not suitable for surgery.
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spelling pubmed-91983002022-06-16 Case Report: Treatment of Hypertrophic Cardiomyopathy With Stereotactic Body Radiotherapy Xiao, Longzihui Liu, Jiayi Zhang, Yingzhe Liu, Yuefei Tang, Yan Zhang, Minping Ding, Zhuyuan Xiao, Enhua Chen, Taili Front Med (Lausanne) Medicine Patients with hypertrophic cardiomyopathy (HCM), which is characterized by left ventricular hypertrophy, is usually treated with medications such as calcium channel blockers or beta-blockers and invasive treatments such as transcatheter alcohol septal ablation, percutaneous radiofrequency ablation, or heart transplantation. However, non-invasive methods have not been employed for the management of patients with HCM. A 71-year-old male who presented with occasional chest pain for approximately 2 months and had been diagnosed with HCM since he was 39 years old due to occasional fainting was treated with a novel method for HCM using stereotactic body radiotherapy (SBRT). The administration of 25 Gy of radiation as one fraction led to an improvement in his quality of life. No toxicity occurred during or immediately after the treatment. Our observations suggest that SBRT may be a reasonable treatment approach for patients with HCM who are not suitable for surgery. Frontiers Media S.A. 2022-06-01 /pmc/articles/PMC9198300/ /pubmed/35721064 http://dx.doi.org/10.3389/fmed.2022.799310 Text en Copyright © 2022 Xiao, Liu, Zhang, Liu, Tang, Zhang, Ding, Xiao and Chen. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Medicine
Xiao, Longzihui
Liu, Jiayi
Zhang, Yingzhe
Liu, Yuefei
Tang, Yan
Zhang, Minping
Ding, Zhuyuan
Xiao, Enhua
Chen, Taili
Case Report: Treatment of Hypertrophic Cardiomyopathy With Stereotactic Body Radiotherapy
title Case Report: Treatment of Hypertrophic Cardiomyopathy With Stereotactic Body Radiotherapy
title_full Case Report: Treatment of Hypertrophic Cardiomyopathy With Stereotactic Body Radiotherapy
title_fullStr Case Report: Treatment of Hypertrophic Cardiomyopathy With Stereotactic Body Radiotherapy
title_full_unstemmed Case Report: Treatment of Hypertrophic Cardiomyopathy With Stereotactic Body Radiotherapy
title_short Case Report: Treatment of Hypertrophic Cardiomyopathy With Stereotactic Body Radiotherapy
title_sort case report: treatment of hypertrophic cardiomyopathy with stereotactic body radiotherapy
topic Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9198300/
https://www.ncbi.nlm.nih.gov/pubmed/35721064
http://dx.doi.org/10.3389/fmed.2022.799310
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