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Development of UPLC-MS/MS method and its pharmacokinetic application for estimation of sertraline in rat plasma
The current research aims to develop a rapid, sensitive and robust UPLC-MS/MS method for quantitative estimation of sertraline in rat plasma following oral administration of lipid-based formulation. Different types of isocratic systems were tried for optimization of mobile phase to attain good resol...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9198327/ https://www.ncbi.nlm.nih.gov/pubmed/35720168 http://dx.doi.org/10.1016/j.mex.2022.101750 |