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Selective B cell depletion upon intravenous infusion of replication-incompetent anti-CD19 CAR lentivirus

Anti-CD19 chimeric antigen receptor (CAR)-T therapy for B cell malignancies has shown clinical success, but a major limitation is the logistical complexity and high cost of manufacturing autologous cell products. If engineered for improved safety, direct infusion of viral gene transfer vectors to in...

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Detalles Bibliográficos
Autores principales:	Rive, Craig M., Yung, Eric, Dreolini, Lisa, Brown, Scott D., May, Christopher G., Woodsworth, Daniel J., Holt, Robert A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9198363/ https://www.ncbi.nlm.nih.gov/pubmed/35755944 http://dx.doi.org/10.1016/j.omtm.2022.05.006

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