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Pharmacological Melanocortin 5 Receptor Activation Attenuates Glomerular Injury and Proteinuria in Rats With Puromycin Aminonucleoside Nephrosis

Clinical evidence indicates that the melanocortin peptide ACTH is effective in inducing remission of nephrotic glomerulopathies like minimal change disease (MCD) and focal segmental glomerulosclerosis (FSGS), including those resistant to steroids. This suggests that a steroid-independent melancortin...

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Detalles Bibliográficos
Autores principales: Chen, Bohan, Alam, Zubia, Ge, Yan, Dworkin, Lance, Gong, Rujun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9198460/
https://www.ncbi.nlm.nih.gov/pubmed/35721571
http://dx.doi.org/10.3389/fphys.2022.887641