Concerted actions of DnaA complexes with DNA-unwinding sequences within and flanking replication origin oriC promote DnaB helicase loading

Unwinding of the replication origin and loading of DNA helicases underlie the initiation of chromosomal replication. In Escherichia coli, the minimal origin oriC contains a duplex unwinding element (DUE) region and three (Left, Middle, and Right) regions that bind the initiator protein DnaA. The Lef...

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Detalles Bibliográficos
Autores principales: Sakiyama, Yukari, Nagata, Mariko, Yoshida, Ryusei, Kasho, Kazutoshi, Ozaki, Shogo, Katayama, Tsutomu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9198467/
https://www.ncbi.nlm.nih.gov/pubmed/35598828
http://dx.doi.org/10.1016/j.jbc.2022.102051

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