The Key Role of RNA Modification in Breast Cancer

The modulation of the function and expression of epigenetic regulators of RNA modification has gradually become the hotspot of cancer research. Studies have shown that alteration of epigenetic modifications can promote the development and metastasis of breast cancer. This review highlights the progr...

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Detalles Bibliográficos
Autores principales: Liu, Yang, Zhu, Tong, Jiang, Yi, Bu, Jiawen, Zhu, Xudong, Gu, Xi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9198488/
https://www.ncbi.nlm.nih.gov/pubmed/35721510
http://dx.doi.org/10.3389/fcell.2022.885133
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author Liu, Yang
Zhu, Tong
Jiang, Yi
Bu, Jiawen
Zhu, Xudong
Gu, Xi
author_facet Liu, Yang
Zhu, Tong
Jiang, Yi
Bu, Jiawen
Zhu, Xudong
Gu, Xi
author_sort Liu, Yang
collection PubMed
description The modulation of the function and expression of epigenetic regulators of RNA modification has gradually become the hotspot of cancer research. Studies have shown that alteration of epigenetic modifications can promote the development and metastasis of breast cancer. This review highlights the progress in characterization of the link between RNA modification and the prognosis, carcinogenesis and treatment of breast cancer, which may provide a new theoretical basis for development of effective strategies for monitoring of breast cancer based on epigenetics.
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spelling pubmed-91984882022-06-16 The Key Role of RNA Modification in Breast Cancer Liu, Yang Zhu, Tong Jiang, Yi Bu, Jiawen Zhu, Xudong Gu, Xi Front Cell Dev Biol Cell and Developmental Biology The modulation of the function and expression of epigenetic regulators of RNA modification has gradually become the hotspot of cancer research. Studies have shown that alteration of epigenetic modifications can promote the development and metastasis of breast cancer. This review highlights the progress in characterization of the link between RNA modification and the prognosis, carcinogenesis and treatment of breast cancer, which may provide a new theoretical basis for development of effective strategies for monitoring of breast cancer based on epigenetics. Frontiers Media S.A. 2022-06-01 /pmc/articles/PMC9198488/ /pubmed/35721510 http://dx.doi.org/10.3389/fcell.2022.885133 Text en Copyright © 2022 Liu, Zhu, Jiang, Bu, Zhu and Gu. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cell and Developmental Biology
Liu, Yang
Zhu, Tong
Jiang, Yi
Bu, Jiawen
Zhu, Xudong
Gu, Xi
The Key Role of RNA Modification in Breast Cancer
title The Key Role of RNA Modification in Breast Cancer
title_full The Key Role of RNA Modification in Breast Cancer
title_fullStr The Key Role of RNA Modification in Breast Cancer
title_full_unstemmed The Key Role of RNA Modification in Breast Cancer
title_short The Key Role of RNA Modification in Breast Cancer
title_sort key role of rna modification in breast cancer
topic Cell and Developmental Biology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9198488/
https://www.ncbi.nlm.nih.gov/pubmed/35721510
http://dx.doi.org/10.3389/fcell.2022.885133
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