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Platelet Activation in Ocular Behçet’s Patients with Posterior Segment Involvement
PURPOSE: The aim of the present study was to assess platelet activation by analyzing three platelet activation parameters in ocular Behçet's disease (BD): mean platelet volume (MPV), platelet distribution width (PDW), and plateletcrit (PCT). METHODS: Twenty-nine patients with active ocular BD (...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9198532/ https://www.ncbi.nlm.nih.gov/pubmed/35719287 http://dx.doi.org/10.4103/meajo.MEAJO_324_19 |
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author | Citirik, Mehmet Ozdal, Pinar C. Keles, Ali Haznedaroglu, Ibrahim C. |
author_facet | Citirik, Mehmet Ozdal, Pinar C. Keles, Ali Haznedaroglu, Ibrahim C. |
author_sort | Citirik, Mehmet |
collection | PubMed |
description | PURPOSE: The aim of the present study was to assess platelet activation by analyzing three platelet activation parameters in ocular Behçet's disease (BD): mean platelet volume (MPV), platelet distribution width (PDW), and plateletcrit (PCT). METHODS: Twenty-nine patients with active ocular BD (Group 1), 40 patients with inactive ocular BD (Group 2), and 40 healthy adult individuals serving as controls (Group 3) were evaluated. All of the individuals had been performed the complete ophthalmologic evaluation. The levels of MPV, PDW, and PCT were measured in each group. RESULTS: The mean MPV level was 8.40 ± 0.97 in Group 1, 8.32 ± 1.04 in Group 2, and 7.77 ± 0.72 in Group 3. The mean PDW level was 15.12 ± 1.09 in Group 1, 14.97 ± 1.02 in Group 2, and 14.52 ± 0.82 in Group 3. The mean PCT level was 0.23 ± 0.07 in Group 1, 0.21 ± 0.04 in Group 2, and 0.18 ± 0.03 in Group 3. MPV, PDW, and PCT levels were significantly higher in ocular BD patients than controls (P < 0.05). CONCLUSION: Platelet activation may affect vascular occlusion in ocular Behçet's patients with posterior segment involvement. This result may be important in evaluating ocular BD patients. |
format | Online Article Text |
id | pubmed-9198532 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-91985322022-06-16 Platelet Activation in Ocular Behçet’s Patients with Posterior Segment Involvement Citirik, Mehmet Ozdal, Pinar C. Keles, Ali Haznedaroglu, Ibrahim C. Middle East Afr J Ophthalmol Original Article PURPOSE: The aim of the present study was to assess platelet activation by analyzing three platelet activation parameters in ocular Behçet's disease (BD): mean platelet volume (MPV), platelet distribution width (PDW), and plateletcrit (PCT). METHODS: Twenty-nine patients with active ocular BD (Group 1), 40 patients with inactive ocular BD (Group 2), and 40 healthy adult individuals serving as controls (Group 3) were evaluated. All of the individuals had been performed the complete ophthalmologic evaluation. The levels of MPV, PDW, and PCT were measured in each group. RESULTS: The mean MPV level was 8.40 ± 0.97 in Group 1, 8.32 ± 1.04 in Group 2, and 7.77 ± 0.72 in Group 3. The mean PDW level was 15.12 ± 1.09 in Group 1, 14.97 ± 1.02 in Group 2, and 14.52 ± 0.82 in Group 3. The mean PCT level was 0.23 ± 0.07 in Group 1, 0.21 ± 0.04 in Group 2, and 0.18 ± 0.03 in Group 3. MPV, PDW, and PCT levels were significantly higher in ocular BD patients than controls (P < 0.05). CONCLUSION: Platelet activation may affect vascular occlusion in ocular Behçet's patients with posterior segment involvement. This result may be important in evaluating ocular BD patients. Wolters Kluwer - Medknow 2022-04-30 /pmc/articles/PMC9198532/ /pubmed/35719287 http://dx.doi.org/10.4103/meajo.MEAJO_324_19 Text en Copyright: © 2022 Middle East African Journal of Ophthalmology https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Citirik, Mehmet Ozdal, Pinar C. Keles, Ali Haznedaroglu, Ibrahim C. Platelet Activation in Ocular Behçet’s Patients with Posterior Segment Involvement |
title | Platelet Activation in Ocular Behçet’s Patients with Posterior Segment Involvement |
title_full | Platelet Activation in Ocular Behçet’s Patients with Posterior Segment Involvement |
title_fullStr | Platelet Activation in Ocular Behçet’s Patients with Posterior Segment Involvement |
title_full_unstemmed | Platelet Activation in Ocular Behçet’s Patients with Posterior Segment Involvement |
title_short | Platelet Activation in Ocular Behçet’s Patients with Posterior Segment Involvement |
title_sort | platelet activation in ocular behçet’s patients with posterior segment involvement |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9198532/ https://www.ncbi.nlm.nih.gov/pubmed/35719287 http://dx.doi.org/10.4103/meajo.MEAJO_324_19 |
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