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CAR T Cells Targeting Membrane-Bound Hsp70 on Tumor Cells Mimic Hsp70-Primed NK Cells

Strategies to boost anti-tumor immunity are urgently needed to treat therapy-resistant late-stage cancers, including colorectal cancers (CRCs). Cytokine stimulation and genetic modifications with chimeric antigen receptors (CAR) represent promising strategies to more specifically redirect anti-tumor...

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Detalles Bibliográficos
Autores principales: Bashiri Dezfouli, Ali, Yazdi, Mina, Benmebarek, Mohamed-Reda, Schwab, Melissa, Michaelides, Stefanos, Miccichè, Arianna, Geerts, Dirk, Stangl, Stefan, Klapproth, Sarah, Wagner, Ernst, Kobold, Sebastian, Multhoff, Gabriele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9198541/
https://www.ncbi.nlm.nih.gov/pubmed/35720311
http://dx.doi.org/10.3389/fimmu.2022.883694