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Gene Coexpression Network Characterizing Microenvironmental Heterogeneity and Intercellular Communication in Pancreatic Ductal Adenocarcinoma: Implications of Prognostic Significance and Therapeutic Target

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is characterized by intensive stromal involvement and heterogeneity. Pancreatic cancer cells interact with the surrounding tumor microenvironment (TME), leading to tumor development, unfavorable prognosis, and therapy resistance. Herein, we aim to...

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Detalles Bibliográficos
Autores principales: Wu, Chengsi, Liu, Yizhen, Wei, Dianhui, Tao, Li, Yuan, Lili, Jing, Tiantian, Wang, Boshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9198606/
https://www.ncbi.nlm.nih.gov/pubmed/35719923
http://dx.doi.org/10.3389/fonc.2022.840474