A dPCR-NIPT assay for detections of trisomies 21, 18 and 13 in a single-tube reaction-could it replace serum biochemical tests as a primary maternal plasma screening tool?

BACKGROUND: The next generation sequencing (NGS) based non-invasive prenatal test (NIPT) has outplayed the traditional serum biochemical tests (SBT) in screen of fetal aneuploidies with a high sensitivity and specificity. However, it has not been widely used as a primary screen tool due to its high...

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Detalles Bibliográficos
Autores principales: Dai, Peng, Yang, Yanfeng, Zhao, Ganye, Gu, Zhiqiang, Ren, Huanan, Hu, Shuang, Liu, Ning, Jiao, Weimeng, Li, Jinfang, Kong, Xiangdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9198625/
https://www.ncbi.nlm.nih.gov/pubmed/35706031
http://dx.doi.org/10.1186/s12967-022-03455-y

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