HIV-1 mutants that escape the cytotoxic T-lymphocytes are defective in viral DNA integration

HIV-1 replication is durably controlled without antiretroviral therapy (ART) in certain infected individuals called elite controllers (ECs). These individuals express specific human leukocyte antigens (HLA) that tag HIV-infected cells for elimination by presenting viral epitopes to CD8+ cytotoxic T-...

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Detalles Bibliográficos
Autores principales: Balasubramaniam, Muthukumar, Davids, Benem-Orom, Bryer, Alex, Xu, Chaoyi, Thapa, Santosh, Shi, Jiong, Aiken, Christopher, Pandhare, Jui, Perilla, Juan R, Dash, Chandravanu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Biological, Health, and Medical Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9198661/
https://www.ncbi.nlm.nih.gov/pubmed/35719891
http://dx.doi.org/10.1093/pnasnexus/pgac064

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