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PTEN-Induced Putative Kinase 1 Dysfunction Accelerates Synucleinopathy

BACKGROUND: Mutations in PTEN-induced putative kinase 1 (PINK1) cause autosomal recessive Parkinson’s disease (PD) and contribute to the risk of sporadic PD. However, the relationship between PD-related PINK1 mutations and alpha-synuclein (α-syn) aggregation—a main pathological component of PD—remai...

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Detalles Bibliográficos
Autores principales:	Nguyen, Tinh Thi, Kim, Yun Joong, Lai, Thuy Thi, Nguyen, Phuong Thi, Koh, Young Ho, Nguyen, Linh Thi Nhat, Ma, Hyeo-il, Kim, Young Eun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	IOS Press 2022
Materias:	Research Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9198758/ https://www.ncbi.nlm.nih.gov/pubmed/35253778 http://dx.doi.org/10.3233/JPD-213065

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