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A complex proinflammatory cascade mediates the activation of HSCs upon LPS exposure in vivo
Infections are a key source of stress to the hematopoietic system. While infections consume short-lived innate immune cells, their recovery depends on quiescent hematopoietic stem cells (HSCs) with long-term self-renewal capacity. Both chronic inflammatory stress and bacterial infections compromise...
Autores principales: | Demel, Uta Margareta, Lutz, Raphael, Sujer, Stefanie, Demerdash, Yasmin, Sood, Shubhankar, Grünschläger, Florian, Kuck, Andrea, Werner, Paula, Blaszkiewicz, Sandra, Uckelmann, Hannah Julia, Haas, Simon, Essers, Marieke Alida Gertruda |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Hematology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9198917/ https://www.ncbi.nlm.nih.gov/pubmed/35413096 http://dx.doi.org/10.1182/bloodadvances.2021006088 |
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