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Deep sequencing in CD34(+) cells from peripheral blood enables sensitive detection of measurable residual disease in AML
Monitoring of measurable residual disease (MRD) in patients with acute myeloid leukemia (AML) is predictive of disease recurrence and may identify patients who benefit from treatment intensification. Current MRD techniques rely on multicolor flow cytometry or molecular methods, but are limited in ap...
Autores principales: | Stasik, Sebastian, Burkhard-Meier, Clara, Kramer, Michael, Middeke, Jan M., Oelschlaegel, Uta, Sockel, Katja, Ehninger, Gerhard, Serve, Hubert, Müller-Tidow, Carsten, Baldus, Claudia D., Röllig, Christoph, Bornhäuser, Martin, Platzbecker, Uwe, Thiede, Christian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Hematology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9198930/ https://www.ncbi.nlm.nih.gov/pubmed/35320339 http://dx.doi.org/10.1182/bloodadvances.2021006233 |
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