Ubiquitinating the way to T cell metabolism

In this issue, Harris et al. (2022. J. Cell Biol. https://doi.org/10.1083/jcb.202203095) show that phosphofructokinase is a substrate for ubiquitination by Fbxo7, a key protein in the ubiquitination pathway. Their findings point to a new interplay between metabolic enzyme degradation in the regulati...

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Detalles Bibliográficos
Autores principales: McPhedran, Sarah, Lum, Julian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Spotlight
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9198946/
https://www.ncbi.nlm.nih.gov/pubmed/35695892
http://dx.doi.org/10.1083/jcb.202206006
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author McPhedran, Sarah
Lum, Julian J.
author_facet McPhedran, Sarah
Lum, Julian J.
author_sort McPhedran, Sarah
collection PubMed
description In this issue, Harris et al. (2022. J. Cell Biol. https://doi.org/10.1083/jcb.202203095) show that phosphofructokinase is a substrate for ubiquitination by Fbxo7, a key protein in the ubiquitination pathway. Their findings point to a new interplay between metabolic enzyme degradation in the regulation of T cells.
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spelling pubmed-91989462023-01-04 Ubiquitinating the way to T cell metabolism McPhedran, Sarah Lum, Julian J. J Cell Biol Spotlight In this issue, Harris et al. (2022. J. Cell Biol. https://doi.org/10.1083/jcb.202203095) show that phosphofructokinase is a substrate for ubiquitination by Fbxo7, a key protein in the ubiquitination pathway. Their findings point to a new interplay between metabolic enzyme degradation in the regulation of T cells. Rockefeller University Press 2022-06-13 /pmc/articles/PMC9198946/ /pubmed/35695892 http://dx.doi.org/10.1083/jcb.202206006 Text en © 2022 McPhedran and Lum https://creativecommons.org/licenses/by-nc-sa/4.0/http://www.rupress.org/terms/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Spotlight
McPhedran, Sarah
Lum, Julian J.
Ubiquitinating the way to T cell metabolism
title Ubiquitinating the way to T cell metabolism
title_full Ubiquitinating the way to T cell metabolism
title_fullStr Ubiquitinating the way to T cell metabolism
title_full_unstemmed Ubiquitinating the way to T cell metabolism
title_short Ubiquitinating the way to T cell metabolism
title_sort ubiquitinating the way to t cell metabolism
topic Spotlight
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9198946/
https://www.ncbi.nlm.nih.gov/pubmed/35695892
http://dx.doi.org/10.1083/jcb.202206006
work_keys_str_mv AT mcphedransarah ubiquitinatingthewaytotcellmetabolism
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