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Prevention of acute graft-vs.-host disease by targeting glycolysis and mTOR pathways in activated T cells

Graft-versus-host disease (GvHD) is a common life-threatening complication that can occur following allogeneic hematopoietic stem cell transplantation. This occurs if donor T cells recognize the host as foreign. During acute GvHD (aGVHD), activated T cells utilize glycolysis as the main source of en...

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Detalles Bibliográficos
Autores principales: Zhou, Rui-Qing, Wang, Xiaobo, Ye, Yong-Bin, Lu, Bo, Wang, Jing, Guo, Zi-Wen, Mo, Wen-Jian, Yang, Zheng, Srisuk, Pathomthat, Yan, Le-Ping, Xu, Xiao-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9199067/
https://www.ncbi.nlm.nih.gov/pubmed/35720623
http://dx.doi.org/10.3892/etm.2022.11375