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Prevention of acute graft-vs.-host disease by targeting glycolysis and mTOR pathways in activated T cells
Graft-versus-host disease (GvHD) is a common life-threatening complication that can occur following allogeneic hematopoietic stem cell transplantation. This occurs if donor T cells recognize the host as foreign. During acute GvHD (aGVHD), activated T cells utilize glycolysis as the main source of en...
Autores principales: | Zhou, Rui-Qing, Wang, Xiaobo, Ye, Yong-Bin, Lu, Bo, Wang, Jing, Guo, Zi-Wen, Mo, Wen-Jian, Yang, Zheng, Srisuk, Pathomthat, Yan, Le-Ping, Xu, Xiao-Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9199067/ https://www.ncbi.nlm.nih.gov/pubmed/35720623 http://dx.doi.org/10.3892/etm.2022.11375 |
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