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Hydroxychloroquine induces apoptosis of myeloid-derived suppressor cells via up-regulation of CD81 contributing to alleviate lupus symptoms

BACKGROUND: Systemic lupus erythematosus (SLE) is a chronic autoimmune disorder that results from widespread immune complex deposition and secondary tissue injury. Hydroxychloroquine (HCQ) has been used clinically to treat SLE, while its exact mechanism has still remained elusive. Some studies have...

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Detalles Bibliográficos
Autores principales:	Ni, Jiali, Zhu, Haiyan, Lu, Li, Zhao, Zihe, Jiang, Jiaxuan, You, Xiaokang, Wang, Yuzhu, Ma, Yuliang, Yang, Zirui, Hou, Yayi, Dou, Huan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9199128/ https://www.ncbi.nlm.nih.gov/pubmed/35705919 http://dx.doi.org/10.1186/s10020-022-00493-6

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