NEK2 promotes the migration and proliferation of ESCC via stabilization of YAP1 by phosphorylation at Thr-143

BACKGROUND: Esophageal Squamous Cell Carcinoma (ESCC) was characterized as a regional-prevalent and aggressive tumor with high morbidity and mortality. NIMA-related kinase 2 (NEK2) is an interesting oncogene, the alteration of which leads to patients-beneficial outcomes. We aimed to explore the role...

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Detalles Bibliográficos
Autores principales: Su, Wei, Hu, Hao, Ding, Qiurong, Wang, Min, Zhu, Yan, Zhang, Zhaochao, Geng, Zihan, Lin, Shengli, Zhou, Pinghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9199137/
https://www.ncbi.nlm.nih.gov/pubmed/35705994
http://dx.doi.org/10.1186/s12964-022-00898-0

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