Early-life stress elicits peripheral and brain immune activation differently in wild type and 5xFAD mice in a sex-specific manner

BACKGROUND: The risk of developing Alzheimer’s disease (AD) is modulated by genetic and environmental factors. Early-life stress (ELS) exposure during critical periods of brain development can impact later brain function and health, including increasing the risk of developing AD. Microglial dysfunct...

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Detalles Bibliográficos
Autores principales: Bachiller, S., Hidalgo, I., Garcia, M. G., Boza-Serrano, A., Paulus, A., Denis, Q., Haikal, C., Manouchehrian, O., Klementieva, O., Li, J. Y., Pronk, C. J., Gouras, G. K., Deierborg, T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9199174/
https://www.ncbi.nlm.nih.gov/pubmed/35705972
http://dx.doi.org/10.1186/s12974-022-02515-w

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