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Superior control of inflammatory pain by corticotropin-releasing factor receptor 1 via opioid peptides in distinct pain-relevant brain areas

BACKGROUND: Under inflammatory conditions, the activation of corticotropin-releasing factor (CRF) receptor has been shown to inhibit pain through opioid peptide release from immune cells or neurons. CRF’s effects on human and animal pain modulation depend, however, on the distribution of its recepto...

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Detalles Bibliográficos
Autores principales: Mousa, Shaaban A., Khalefa, Baled I., Shaqura, Mohammed, Al-Madol, Mohammed, Treskatsch, Sascha, Schäfer, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9199204/
https://www.ncbi.nlm.nih.gov/pubmed/35705992
http://dx.doi.org/10.1186/s12974-022-02498-8

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