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Automated detection of anterior cruciate ligament tears using a deep convolutional neural network

BACKGROUND: The development of computer-assisted technologies to diagnose anterior cruciate ligament (ACL) injury by analyzing knee magnetic resonance images (MRI) would be beneficial, and convolutional neural network (CNN)-based deep learning approaches may offer a solution. This study aimed to eva...

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Autores principales: Minamoto, Yusuke, Akagi, Ryuichiro, Maki, Satoshi, Shiko, Yuki, Tozawa, Ryosuke, Kimura, Seiji, Yamaguchi, Satoshi, Kawasaki, Yohei, Ohtori, Seiji, Sasho, Takahisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9199233/
https://www.ncbi.nlm.nih.gov/pubmed/35705930
http://dx.doi.org/10.1186/s12891-022-05524-1
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author Minamoto, Yusuke
Akagi, Ryuichiro
Maki, Satoshi
Shiko, Yuki
Tozawa, Ryosuke
Kimura, Seiji
Yamaguchi, Satoshi
Kawasaki, Yohei
Ohtori, Seiji
Sasho, Takahisa
author_facet Minamoto, Yusuke
Akagi, Ryuichiro
Maki, Satoshi
Shiko, Yuki
Tozawa, Ryosuke
Kimura, Seiji
Yamaguchi, Satoshi
Kawasaki, Yohei
Ohtori, Seiji
Sasho, Takahisa
author_sort Minamoto, Yusuke
collection PubMed
description BACKGROUND: The development of computer-assisted technologies to diagnose anterior cruciate ligament (ACL) injury by analyzing knee magnetic resonance images (MRI) would be beneficial, and convolutional neural network (CNN)-based deep learning approaches may offer a solution. This study aimed to evaluate the accuracy of a CNN system in diagnosing ACL ruptures by a single slice from a knee MRI and to compare the results with that of experienced human readers. METHODS: One hundred sagittal MR images from patients with and without ACL injuries, confirmed by arthroscopy, were cropped and used for the CNN training. The final decision by the CNN for intact or torn ACL was based on the probability of ACL tear on a single MRI slice. Twelve board-certified physicians reviewed the same images used by CNN. RESULTS: The sensitivity, specificity, accuracy, positive predictive value and negative predictive value of the CNN classification was 91.0%, 86.0%, 88.5%, 87.0%, and 91.0%, respectively. The overall values of the physicians’ readings were similar, but the specificity was lower than the CNN classification for some of the physicians, thus resulting in lower accuracy for the human readers. CONCLUSIONS: The trained CNN automatically detected the ACL tears with acceptable accuracy comparable to that of human readers.
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spelling pubmed-91992332022-06-16 Automated detection of anterior cruciate ligament tears using a deep convolutional neural network Minamoto, Yusuke Akagi, Ryuichiro Maki, Satoshi Shiko, Yuki Tozawa, Ryosuke Kimura, Seiji Yamaguchi, Satoshi Kawasaki, Yohei Ohtori, Seiji Sasho, Takahisa BMC Musculoskelet Disord Research BACKGROUND: The development of computer-assisted technologies to diagnose anterior cruciate ligament (ACL) injury by analyzing knee magnetic resonance images (MRI) would be beneficial, and convolutional neural network (CNN)-based deep learning approaches may offer a solution. This study aimed to evaluate the accuracy of a CNN system in diagnosing ACL ruptures by a single slice from a knee MRI and to compare the results with that of experienced human readers. METHODS: One hundred sagittal MR images from patients with and without ACL injuries, confirmed by arthroscopy, were cropped and used for the CNN training. The final decision by the CNN for intact or torn ACL was based on the probability of ACL tear on a single MRI slice. Twelve board-certified physicians reviewed the same images used by CNN. RESULTS: The sensitivity, specificity, accuracy, positive predictive value and negative predictive value of the CNN classification was 91.0%, 86.0%, 88.5%, 87.0%, and 91.0%, respectively. The overall values of the physicians’ readings were similar, but the specificity was lower than the CNN classification for some of the physicians, thus resulting in lower accuracy for the human readers. CONCLUSIONS: The trained CNN automatically detected the ACL tears with acceptable accuracy comparable to that of human readers. BioMed Central 2022-06-15 /pmc/articles/PMC9199233/ /pubmed/35705930 http://dx.doi.org/10.1186/s12891-022-05524-1 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Minamoto, Yusuke
Akagi, Ryuichiro
Maki, Satoshi
Shiko, Yuki
Tozawa, Ryosuke
Kimura, Seiji
Yamaguchi, Satoshi
Kawasaki, Yohei
Ohtori, Seiji
Sasho, Takahisa
Automated detection of anterior cruciate ligament tears using a deep convolutional neural network
title Automated detection of anterior cruciate ligament tears using a deep convolutional neural network
title_full Automated detection of anterior cruciate ligament tears using a deep convolutional neural network
title_fullStr Automated detection of anterior cruciate ligament tears using a deep convolutional neural network
title_full_unstemmed Automated detection of anterior cruciate ligament tears using a deep convolutional neural network
title_short Automated detection of anterior cruciate ligament tears using a deep convolutional neural network
title_sort automated detection of anterior cruciate ligament tears using a deep convolutional neural network
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9199233/
https://www.ncbi.nlm.nih.gov/pubmed/35705930
http://dx.doi.org/10.1186/s12891-022-05524-1
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