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Dissociative Symptoms and Disorders in Patients With Bipolar Disorders: A Scoping Review

Dissociative disorders are an important group of trauma-related disorders associated with significant disability. The co-occurrence of dissociative disorders (DD) and symptoms (DS) in bipolar disorder has been relatively understudied, but there is some evidence that this comorbidity may have signifi...

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Autor principal: Rajkumar, Ravi Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9199377/
https://www.ncbi.nlm.nih.gov/pubmed/35722564
http://dx.doi.org/10.3389/fpsyt.2022.925983
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author Rajkumar, Ravi Philip
author_facet Rajkumar, Ravi Philip
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description Dissociative disorders are an important group of trauma-related disorders associated with significant disability. The co-occurrence of dissociative disorders (DD) and symptoms (DS) in bipolar disorder has been relatively understudied, but there is some evidence that this comorbidity may have significant mechanistic and clinical implications. This paper presents the results of a scoping review of the frequency and correlates of DS and DD in bipolar disorder. Based on the available evidence, DS/DD are more common in bipolar disorder than in healthy controls or in unipolar depression, are related to childhood trauma, and are associated with psychotic symptoms, suicide attempts, and a poorer response to treatment in patients with bipolar disorder. The implications of these findings, and possible mechanistic pathways underlying them, are discussed based on the current literature. Clinicians should be aware of the frequent occurrence of significant DS or DD when treating patients with bipolar disorder. A tentative future research agenda for this field, based on clinical, risk factor-related and neurobiological considerations, is outlined.
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spelling pubmed-91993772022-06-16 Dissociative Symptoms and Disorders in Patients With Bipolar Disorders: A Scoping Review Rajkumar, Ravi Philip Front Psychiatry Psychiatry Dissociative disorders are an important group of trauma-related disorders associated with significant disability. The co-occurrence of dissociative disorders (DD) and symptoms (DS) in bipolar disorder has been relatively understudied, but there is some evidence that this comorbidity may have significant mechanistic and clinical implications. This paper presents the results of a scoping review of the frequency and correlates of DS and DD in bipolar disorder. Based on the available evidence, DS/DD are more common in bipolar disorder than in healthy controls or in unipolar depression, are related to childhood trauma, and are associated with psychotic symptoms, suicide attempts, and a poorer response to treatment in patients with bipolar disorder. The implications of these findings, and possible mechanistic pathways underlying them, are discussed based on the current literature. Clinicians should be aware of the frequent occurrence of significant DS or DD when treating patients with bipolar disorder. A tentative future research agenda for this field, based on clinical, risk factor-related and neurobiological considerations, is outlined. Frontiers Media S.A. 2022-05-26 /pmc/articles/PMC9199377/ /pubmed/35722564 http://dx.doi.org/10.3389/fpsyt.2022.925983 Text en Copyright © 2022 Rajkumar. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Psychiatry
Rajkumar, Ravi Philip
Dissociative Symptoms and Disorders in Patients With Bipolar Disorders: A Scoping Review
title Dissociative Symptoms and Disorders in Patients With Bipolar Disorders: A Scoping Review
title_full Dissociative Symptoms and Disorders in Patients With Bipolar Disorders: A Scoping Review
title_fullStr Dissociative Symptoms and Disorders in Patients With Bipolar Disorders: A Scoping Review
title_full_unstemmed Dissociative Symptoms and Disorders in Patients With Bipolar Disorders: A Scoping Review
title_short Dissociative Symptoms and Disorders in Patients With Bipolar Disorders: A Scoping Review
title_sort dissociative symptoms and disorders in patients with bipolar disorders: a scoping review
topic Psychiatry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9199377/
https://www.ncbi.nlm.nih.gov/pubmed/35722564
http://dx.doi.org/10.3389/fpsyt.2022.925983
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