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Dissociative Symptoms and Disorders in Patients With Bipolar Disorders: A Scoping Review
Dissociative disorders are an important group of trauma-related disorders associated with significant disability. The co-occurrence of dissociative disorders (DD) and symptoms (DS) in bipolar disorder has been relatively understudied, but there is some evidence that this comorbidity may have signifi...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9199377/ https://www.ncbi.nlm.nih.gov/pubmed/35722564 http://dx.doi.org/10.3389/fpsyt.2022.925983 |
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author | Rajkumar, Ravi Philip |
author_facet | Rajkumar, Ravi Philip |
author_sort | Rajkumar, Ravi Philip |
collection | PubMed |
description | Dissociative disorders are an important group of trauma-related disorders associated with significant disability. The co-occurrence of dissociative disorders (DD) and symptoms (DS) in bipolar disorder has been relatively understudied, but there is some evidence that this comorbidity may have significant mechanistic and clinical implications. This paper presents the results of a scoping review of the frequency and correlates of DS and DD in bipolar disorder. Based on the available evidence, DS/DD are more common in bipolar disorder than in healthy controls or in unipolar depression, are related to childhood trauma, and are associated with psychotic symptoms, suicide attempts, and a poorer response to treatment in patients with bipolar disorder. The implications of these findings, and possible mechanistic pathways underlying them, are discussed based on the current literature. Clinicians should be aware of the frequent occurrence of significant DS or DD when treating patients with bipolar disorder. A tentative future research agenda for this field, based on clinical, risk factor-related and neurobiological considerations, is outlined. |
format | Online Article Text |
id | pubmed-9199377 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-91993772022-06-16 Dissociative Symptoms and Disorders in Patients With Bipolar Disorders: A Scoping Review Rajkumar, Ravi Philip Front Psychiatry Psychiatry Dissociative disorders are an important group of trauma-related disorders associated with significant disability. The co-occurrence of dissociative disorders (DD) and symptoms (DS) in bipolar disorder has been relatively understudied, but there is some evidence that this comorbidity may have significant mechanistic and clinical implications. This paper presents the results of a scoping review of the frequency and correlates of DS and DD in bipolar disorder. Based on the available evidence, DS/DD are more common in bipolar disorder than in healthy controls or in unipolar depression, are related to childhood trauma, and are associated with psychotic symptoms, suicide attempts, and a poorer response to treatment in patients with bipolar disorder. The implications of these findings, and possible mechanistic pathways underlying them, are discussed based on the current literature. Clinicians should be aware of the frequent occurrence of significant DS or DD when treating patients with bipolar disorder. A tentative future research agenda for this field, based on clinical, risk factor-related and neurobiological considerations, is outlined. Frontiers Media S.A. 2022-05-26 /pmc/articles/PMC9199377/ /pubmed/35722564 http://dx.doi.org/10.3389/fpsyt.2022.925983 Text en Copyright © 2022 Rajkumar. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Psychiatry Rajkumar, Ravi Philip Dissociative Symptoms and Disorders in Patients With Bipolar Disorders: A Scoping Review |
title | Dissociative Symptoms and Disorders in Patients With Bipolar Disorders: A Scoping Review |
title_full | Dissociative Symptoms and Disorders in Patients With Bipolar Disorders: A Scoping Review |
title_fullStr | Dissociative Symptoms and Disorders in Patients With Bipolar Disorders: A Scoping Review |
title_full_unstemmed | Dissociative Symptoms and Disorders in Patients With Bipolar Disorders: A Scoping Review |
title_short | Dissociative Symptoms and Disorders in Patients With Bipolar Disorders: A Scoping Review |
title_sort | dissociative symptoms and disorders in patients with bipolar disorders: a scoping review |
topic | Psychiatry |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9199377/ https://www.ncbi.nlm.nih.gov/pubmed/35722564 http://dx.doi.org/10.3389/fpsyt.2022.925983 |
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