A Genetic Association Test Accounting for Skewed X-Inactivation With Application to Biotherapy Immunogenicity in Patients With Autoimmune Diseases

Despite being assayed on commercialized DNA chips, the X chromosome is commonly excluded from genome-wide association studies (GWAS). One of the reasons is the complexity to analyze the data taking into account the X-chromosome inactivation (XCI) process in women and in particular the XCI process wi...

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Detalles Bibliográficos
Autores principales: Hässler, Signe, Camilleri-Broët, Sophie, Allez, Matthieu, Deisenhammer, Florian, Fogdell-Hahn, Anna, Mariette, Xavier, Pallardy, Marc, Broët, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9199462/
https://www.ncbi.nlm.nih.gov/pubmed/35721087
http://dx.doi.org/10.3389/fmed.2022.856917

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9199462/
https://www.ncbi.nlm.nih.gov/pubmed/35721087
http://dx.doi.org/10.3389/fmed.2022.856917

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