Cargando…

A Genetic Association Test Accounting for Skewed X-Inactivation With Application to Biotherapy Immunogenicity in Patients With Autoimmune Diseases

Despite being assayed on commercialized DNA chips, the X chromosome is commonly excluded from genome-wide association studies (GWAS). One of the reasons is the complexity to analyze the data taking into account the X-chromosome inactivation (XCI) process in women and in particular the XCI process wi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hässler, Signe, Camilleri-Broët, Sophie, Allez, Matthieu, Deisenhammer, Florian, Fogdell-Hahn, Anna, Mariette, Xavier, Pallardy, Marc, Broët, Philippe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9199462/ https://www.ncbi.nlm.nih.gov/pubmed/35721087 http://dx.doi.org/10.3389/fmed.2022.856917

Ejemplares similares

A Machine Learning Approach for High-Dimensional Time-to-Event Prediction With Application to Immunogenicity of Biotherapies in the ABIRISK Cohort
por: Duhazé, Julianne, et al.
Publicado: (2020)

Assessing the effect of genetic markers on drug immunogenicity from a mechanistic model-based approach
por: Duhazé, Julianne, et al.
Publicado: (2020)

Clinicogenomic factors of biotherapy immunogenicity in autoimmune disease: A prospective multicohort study of the ABIRISK consortium
por: Hässler, Signe, et al.
Publicado: (2020)

Machine learning predicts response to TNF inhibitors in rheumatoid arthritis: results on the ESPOIR and ABIRISK cohorts
por: Bouget, Vincent, et al.
Publicado: (2022)

A score test for comparing cross-sectional survival data with a fraction of non-susceptible patients and its application in clinical immunology
por: Jonas, Sarah Flora, et al.
Publicado: (2017)

Standardizing terms, definitions and concepts for describing and interpreting unwanted immunogenicity of biopharmaceuticals: recommendations of the Innovative Medicines Initiative ABIRISK consortium
por: Rup, B, et al.
Publicado: (2015)

Finding exclusively deleted or amplified genomic areas in lung adenocarcinomas using a novel chromosomal pattern analysis
por: Broët, Philippe, et al.
Publicado: (2009)

Evaluation of the accuracy of the PLCO(m2012) 6-year lung cancer risk prediction model among smokers in the CARTaGENE population-based cohort
por: Jantzen, Rodolphe, et al.
Publicado: (2023)

10(th) European immunogenicity platform open symposium on immunogenicity of biopharmaceuticals
por: Tourdot, S., et al.
Publicado: (2020)

Epidemiological characteristics of the COVID-19 spring outbreak in Quebec, Canada: a population-based study
por: Jantzen, Rodolphe, et al.
Publicado: (2021)

Occurrence of Anti-Drug Antibodies against Interferon-Beta and Natalizumab in Multiple Sclerosis: A Collaborative Cohort Analysis
por: Bachelet, Delphine, et al.
Publicado: (2016)

Clinical practice of analysis of anti-drug antibodies against interferon beta and natalizumab in multiple sclerosis patients in Europe: A descriptive study of test results
por: Link, Jenny, et al.
Publicado: (2017)

Impact de la COVID-19 sur l’initiation des prescriptions des biothérapies dans les maladies inflammatoires chroniques()
por: Richette, Pascal, et al.
Publicado: (2022)

Biotherapies in Uveitis
por: Leclercq, Mathilde, et al.
Publicado: (2020)

56 Prevalence and severity of infections in patients with systemic autoimmune diseases on biotherapy
por: Hiba, Ben Ayed, et al.
Publicado: (2022)

55 Predictive factors of infection in patients with systemic autoimmune disease on biotherapy
por: Manel, Boudokhane, et al.
Publicado: (2022)

Immunogenicity of Anti-TNF-α Biotherapies: I. Individualized Medicine Based on Immunopharmacological Evidence
por: Bendtzen, Klaus
Publicado: (2015)

Analysis of skewed X-chromosome inactivation in females with rheumatoid arthritis and autoimmune thyroid diseases
por: Chabchoub, Ghazi, et al.
Publicado: (2009)

Rituximab in Systemic Lupus Erythematosus: Transient Effects on Autoimmunity Associated Lymphocyte Phenotypes and Implications for Immunogenicity
por: Faustini, Francesca, et al.
Publicado: (2022)

Recent advances of biomaterials in biotherapy
por: Li, Ling, et al.
Publicado: (2016)

Response to Biologic Drugs in Patients With Rheumatoid Arthritis and Antidrug Antibodies
por: Bitoun, Samuel, et al.
Publicado: (2023)

Lack of relationship between EGFR-1 immunohistochemical expression and prognosis in a multicentre clinical trial of 93 patients with advanced primary ovarian epithelial cancer (GINECO group)
por: Elie, C, et al.
Publicado: (2004)

Patterns of chromosomal copy-number alterations in intrahepatic cholangiocarcinoma
por: Dalmasso, Cyril, et al.
Publicado: (2015)

Impact de la COVID-19 sur les initiations et les renouvellements des biothérapies et traitements synthétiques ciblés en France
por: Richette, P., et al.
Publicado: (2020)

A model-based statistic for detecting molecular markers associated with complex survival patterns in early-stage cancer
por: Broët, Philippe, et al.
Publicado: (2012)

Bagging survival tree procedure for variable selection and prediction in the presence of nonsusceptible patients
por: Mbogning, Cyprien, et al.
Publicado: (2016)

HER2 Status in Ovarian Carcinomas: A Multicenter GINECO Study of 320 Patients
por: Tuefferd, Marianne, et al.
Publicado: (2007)

Overview of biotherapy in rheumatoid arthritis (RA)
por: Takeuchi, Tsutomu, et al.
Publicado: (2012)

AB087. The biotherapy for bladder cancer
por: Wang, Zhiping
Publicado: (2015)

Biotherapy in the Adjuvant Treatment of Colorectal Cancer
por: Tazi, El Mehdi, et al.
Publicado: (2011)

Probiotics: A New Era of Biotherapy
por: Alok, Abhijeet, et al.
Publicado: (2017)

Colorectal Cancer, Liver Metastases and Biotherapies
por: Osei-Bordom, Daniel-Clement, et al.
Publicado: (2021)

Immunogenicity of Anti-TNF-α Biotherapies: II. Clinical Relevance of Methods Used for Anti-Drug Antibody Detection
por: Bendtzen, Klaus
Publicado: (2015)

CXCL12 expression by healthy and malignant ovarian epithelial cells
por: Machelon, Véronique, et al.
Publicado: (2011)

Skewed X-chromosome inactivation in patients with esophageal carcinoma
por: Li, Gang, et al.
Publicado: (2013)

Genetic Architecture of Skewed X Inactivation in the Laboratory Mouse
por: Calaway, John D., et al.
Publicado: (2013)

Skewed X-inactivation is common in the general female population
por: Shvetsova, Ekaterina, et al.
Publicado: (2018)

cGAS-STING pathway in cancer biotherapy
por: Wang, Yang, et al.
Publicado: (2020)

COVID-19, asthme sévère et biothérapies
por: Underner, M., et al.
Publicado: (2021)

Identifying common prognostic factors in genomic cancer studies: A novel index for censored outcomes
por: Rouam, Sigrid, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_n734gp4jtm35qeq23b1u96be42