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Dosimetric Superiority of High-Dose-Rate (HDR) Brachytherapy Using a Surface Mold Applicator for Primary Cutaneous Angiosarcoma of the Scalp

The aim of this study was to demonstrate the utility of the dose-volume parameters of the target lesions and the radiation dose to the organ at risk (OAR) in two patients with primary cutaneous angiosarcoma of the scalp (CAS) treated with high-dose-rate brachytherapy (HDR-BT) using a surface mold ap...

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Autores principales: Takase, Kei, Itonaga, Tomohiro, Mikami, Ryuji, Irisawa, Ryokichi, Saito, Kazuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9199566/
https://www.ncbi.nlm.nih.gov/pubmed/35719801
http://dx.doi.org/10.7759/cureus.25056
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author Takase, Kei
Itonaga, Tomohiro
Mikami, Ryuji
Irisawa, Ryokichi
Saito, Kazuhiro
author_facet Takase, Kei
Itonaga, Tomohiro
Mikami, Ryuji
Irisawa, Ryokichi
Saito, Kazuhiro
author_sort Takase, Kei
collection PubMed
description The aim of this study was to demonstrate the utility of the dose-volume parameters of the target lesions and the radiation dose to the organ at risk (OAR) in two patients with primary cutaneous angiosarcoma of the scalp (CAS) treated with high-dose-rate brachytherapy (HDR-BT) using a surface mold applicator. In 2020, two men, aged 80 years and 60 years, respectively, were treated with HDR-BT with paclitaxel for CAS with no distant metastases and no surgical indication at our institution. The total irradiated dose was 57 Gy administered in daily fractions of 3 Gy four days per week. The method of HDR-BT involved the construction of a helmet that fitted over the patient's head, with parallel catheters fixed to the outside at 2.0 cm intervals to transport the iridium-192 HDR-BT source. In conclusion, HDR-BT may be superior when the dose to the target lesion plays a more important role than the OAR dose in selecting radiotherapy modalities for CAS.
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spelling pubmed-91995662022-06-16 Dosimetric Superiority of High-Dose-Rate (HDR) Brachytherapy Using a Surface Mold Applicator for Primary Cutaneous Angiosarcoma of the Scalp Takase, Kei Itonaga, Tomohiro Mikami, Ryuji Irisawa, Ryokichi Saito, Kazuhiro Cureus Dermatology The aim of this study was to demonstrate the utility of the dose-volume parameters of the target lesions and the radiation dose to the organ at risk (OAR) in two patients with primary cutaneous angiosarcoma of the scalp (CAS) treated with high-dose-rate brachytherapy (HDR-BT) using a surface mold applicator. In 2020, two men, aged 80 years and 60 years, respectively, were treated with HDR-BT with paclitaxel for CAS with no distant metastases and no surgical indication at our institution. The total irradiated dose was 57 Gy administered in daily fractions of 3 Gy four days per week. The method of HDR-BT involved the construction of a helmet that fitted over the patient's head, with parallel catheters fixed to the outside at 2.0 cm intervals to transport the iridium-192 HDR-BT source. In conclusion, HDR-BT may be superior when the dose to the target lesion plays a more important role than the OAR dose in selecting radiotherapy modalities for CAS. Cureus 2022-05-16 /pmc/articles/PMC9199566/ /pubmed/35719801 http://dx.doi.org/10.7759/cureus.25056 Text en Copyright © 2022, Takase et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Dermatology
Takase, Kei
Itonaga, Tomohiro
Mikami, Ryuji
Irisawa, Ryokichi
Saito, Kazuhiro
Dosimetric Superiority of High-Dose-Rate (HDR) Brachytherapy Using a Surface Mold Applicator for Primary Cutaneous Angiosarcoma of the Scalp
title Dosimetric Superiority of High-Dose-Rate (HDR) Brachytherapy Using a Surface Mold Applicator for Primary Cutaneous Angiosarcoma of the Scalp
title_full Dosimetric Superiority of High-Dose-Rate (HDR) Brachytherapy Using a Surface Mold Applicator for Primary Cutaneous Angiosarcoma of the Scalp
title_fullStr Dosimetric Superiority of High-Dose-Rate (HDR) Brachytherapy Using a Surface Mold Applicator for Primary Cutaneous Angiosarcoma of the Scalp
title_full_unstemmed Dosimetric Superiority of High-Dose-Rate (HDR) Brachytherapy Using a Surface Mold Applicator for Primary Cutaneous Angiosarcoma of the Scalp
title_short Dosimetric Superiority of High-Dose-Rate (HDR) Brachytherapy Using a Surface Mold Applicator for Primary Cutaneous Angiosarcoma of the Scalp
title_sort dosimetric superiority of high-dose-rate (hdr) brachytherapy using a surface mold applicator for primary cutaneous angiosarcoma of the scalp
topic Dermatology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9199566/
https://www.ncbi.nlm.nih.gov/pubmed/35719801
http://dx.doi.org/10.7759/cureus.25056
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