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The pharmacokinetics of oral trazpiroben (TAK‐906) after organic anion transporting polypeptide 1B1/1B3 inhibition: A phase I, randomized study

Trazpiroben is a dopamine D(2)/D(3) receptor antagonist under development for the treatment of gastroparesis. This phase I, open‐label, randomized, two‐way crossover study (NCT04121078) evaluated the effect of single‐dose intravenous rifampin, a potent inhibitor of the organic anion transporting pol...

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Detalles Bibliográficos
Autores principales:	Mukker, Jatinder K., Dukes, George, Tolkoff, Max, Wang, Lisi, Almansa, Cristina, Huh, Susanna Y., Nishihara, Mitsuhiro, Ramsden, Diane, Chen, Chunlin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9199876/ https://www.ncbi.nlm.nih.gov/pubmed/35460165 http://dx.doi.org/10.1111/cts.13274

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