Evaluation of the relationship between polymorphisms in CYP2C19 and the single‐dose pharmacokinetics of omeprazole in healthy Chinese volunteers: A multicenter study

The aim of this study was to evaluate the relationship between polymorphisms in CYP2C19 and the single‐dose pharmacokinetics (PKs) of omeprazole in healthy Chinese volunteers. A 20 mg single dose of omeprazole (Losec) enteric‐coated capsules or tablets was orally administered to 656 healthy subjects...

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Detalles Bibliográficos
Autores principales: Zhou, Shuang, Xie, Ran, Zhang, Xiaodan, He, Xu, Huang, Jie, Jungang, Yin, Liao, Man, Ding, Ying, Yang, Dandan, Liu, Ying, Zhang, Qian, Yang, Guoping, Liu, Fang, Guan, Shengjiang, He, Qing, Lou, Honggang, Gong, Fengyun, Meng, Xianmin, Xiang, Qian, Zhao, Xia, Cui, Yimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9199891/
https://www.ncbi.nlm.nih.gov/pubmed/35235711
http://dx.doi.org/10.1111/cts.13255

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