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Tuberculosis Aortitis and Mycotic Pseudo-aneurysm of the Infra-renal Aorta after Intravesicular BCG Therapy

We report a patient who presented with a rapidly expanding symptomatic tuberculous aortitis and mycotic pseudo-aneurysm of the infra-renal aorta, after intra-vesical BCG chemotherapy for bladder cancer, treated by required emergency open aneurysm repair. His case highlights this rare complication of...

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Autores principales: Gamble, Nathan, Blair, Robert, Gray, Sam, Hunter, Michael, Harkin, Denis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Ulster Medical Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200094/
https://www.ncbi.nlm.nih.gov/pubmed/35722210
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author Gamble, Nathan
Blair, Robert
Gray, Sam
Hunter, Michael
Harkin, Denis
author_facet Gamble, Nathan
Blair, Robert
Gray, Sam
Hunter, Michael
Harkin, Denis
author_sort Gamble, Nathan
collection PubMed
description We report a patient who presented with a rapidly expanding symptomatic tuberculous aortitis and mycotic pseudo-aneurysm of the infra-renal aorta, after intra-vesical BCG chemotherapy for bladder cancer, treated by required emergency open aneurysm repair. His case highlights this rare complication of intravesical BCG treatment, haematological seeding causing tuberculous aortitis and mycotic pseudo-aneurysm formation of the infra-renal aorta. It also illustrates successful treatment with emergency open surgery, local debridement of mycotic pseudoaneurysm, in-situ surgical reconstruction using a custom bovine-wrap interposition graft to create a neo-aorta and multi-agent anti-tuberculous chemotherapy.
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spelling pubmed-92000942022-06-17 Tuberculosis Aortitis and Mycotic Pseudo-aneurysm of the Infra-renal Aorta after Intravesicular BCG Therapy Gamble, Nathan Blair, Robert Gray, Sam Hunter, Michael Harkin, Denis Ulster Med J Case Report We report a patient who presented with a rapidly expanding symptomatic tuberculous aortitis and mycotic pseudo-aneurysm of the infra-renal aorta, after intra-vesical BCG chemotherapy for bladder cancer, treated by required emergency open aneurysm repair. His case highlights this rare complication of intravesical BCG treatment, haematological seeding causing tuberculous aortitis and mycotic pseudo-aneurysm formation of the infra-renal aorta. It also illustrates successful treatment with emergency open surgery, local debridement of mycotic pseudoaneurysm, in-situ surgical reconstruction using a custom bovine-wrap interposition graft to create a neo-aorta and multi-agent anti-tuberculous chemotherapy. The Ulster Medical Society 2022-06-15 2022-05 /pmc/articles/PMC9200094/ /pubmed/35722210 Text en Copyright © 2022 Ulster Medical Society https://creativecommons.org/licenses/by-nc-sa/4.0/The Ulster Medical Society grants to all users on the basis of a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International Licence the right to alter or build upon the work non-commercially, as long as the author is credited and the new creation is licensed under identical terms.
spellingShingle Case Report
Gamble, Nathan
Blair, Robert
Gray, Sam
Hunter, Michael
Harkin, Denis
Tuberculosis Aortitis and Mycotic Pseudo-aneurysm of the Infra-renal Aorta after Intravesicular BCG Therapy
title Tuberculosis Aortitis and Mycotic Pseudo-aneurysm of the Infra-renal Aorta after Intravesicular BCG Therapy
title_full Tuberculosis Aortitis and Mycotic Pseudo-aneurysm of the Infra-renal Aorta after Intravesicular BCG Therapy
title_fullStr Tuberculosis Aortitis and Mycotic Pseudo-aneurysm of the Infra-renal Aorta after Intravesicular BCG Therapy
title_full_unstemmed Tuberculosis Aortitis and Mycotic Pseudo-aneurysm of the Infra-renal Aorta after Intravesicular BCG Therapy
title_short Tuberculosis Aortitis and Mycotic Pseudo-aneurysm of the Infra-renal Aorta after Intravesicular BCG Therapy
title_sort tuberculosis aortitis and mycotic pseudo-aneurysm of the infra-renal aorta after intravesicular bcg therapy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200094/
https://www.ncbi.nlm.nih.gov/pubmed/35722210
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