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Photosubstitution in a trisheteroleptic ruthenium complex inhibits conjunctival melanoma growth in a zebrafish orthotopic xenograft model

In vivo data are rare but essential for establishing the clinical potential of ruthenium-based photoactivated chemotherapy (PACT) compounds, a new family of phototherapeutic drugs that are activated via ligand photosubstitution. Here a novel trisheteroleptic ruthenium complex [Ru(dpp)(bpy)(mtmp)](PF...

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Detalles Bibliográficos
Autores principales:	Chen, Quanchi, Cuello-Garibo, Jordi-Amat, Bretin, Ludovic, Zhang, Liyan, Ramu, Vadde, Aydar, Yasmin, Batsiun, Yevhen, Bronkhorst, Sharon, Husiev, Yurii, Beztsinna, Nataliia, Chen, Lanpeng, Zhou, Xue-Quan, Schmidt, Claudia, Ott, Ingo, Jager, Martine J., Brouwer, Albert M., Snaar-Jagalska, B. Ewa, Bonnet, Sylvestre
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2022
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200134/ https://www.ncbi.nlm.nih.gov/pubmed/35774173 http://dx.doi.org/10.1039/d2sc01646j

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