A Blunted GPR183/Oxysterol Axis During Dysglycemia Results in Delayed Recruitment of Macrophages to the Lung During Mycobacterium tuberculosis Infection

BACKGROUND: We previously reported that reduced GPR183 expression in blood from tuberculosis (TB) patients with diabetes is associated with more severe TB. METHODS: To further elucidate the role of GPR183 and its oxysterol ligands in the lung, we studied dysglycemic mice infected with Mycobacterium...

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Detalles Bibliográficos
Autores principales: Ngo, Minh Dao, Bartlett, Stacey, Bielefeldt-Ohmann, Helle, Foo, Cheng Xiang, Sinha, Roma, Arachchige, Buddhika Jayakody, Reed, Sarah, Mandrup-Poulsen, Thomas, Rosenkilde, Mette Marie, Ronacher, Katharina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Major Articles and Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200159/
https://www.ncbi.nlm.nih.gov/pubmed/35303091
http://dx.doi.org/10.1093/infdis/jiac102

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