Tet2 coordinates with Foxo1 and Runx1 to balance T follicular helper cell and T helper 1 cell differentiation

In response to various types of infection, naïve CD4(+) T cells differentiate into diverse helper T cell subsets; however, the epigenetic programs that regulate differentiation in response to viral infection remain poorly understood. Demethylation of CpG dinucleotides by Tet methylcytosine dioxygena...

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Detalles Bibliográficos
Autores principales: Baessler, Andrew, Novis, Camille L., Shen, Zuolian, Perovanovic, Jelena, Wadsworth, Mark, Thiede, Kendall A., Sircy, Linda M., Harrison-Chau, Malia, Nguyen, Nguyen X., Varley, Katherine E., Tantin, Dean, Hale, J. Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200277/
https://www.ncbi.nlm.nih.gov/pubmed/35704571
http://dx.doi.org/10.1126/sciadv.abm4982

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